Augmentin '250' and Morphine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Augmentin '250' (amoxicillin; clavulanate potassium) and Morphine (morphine sulfate). Common drug interactions include pneumonia among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Augmentin '250' and Morphine. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Augmentin '250'?

Augmentin '250' has active ingredients of amoxicillin; clavulanate potassium. It is often used in infection. eHealthMe is studying from 502 Augmentin '250' users. Check the latest studies of Augmentin '250'.

What is Morphine?

Morphine has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 182,914 Morphine users. Check the latest studies of Morphine.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 23, 2026

30 people who take Augmentin '250' and Morphine together, and have interactions are studied.

Augmentin '250' and Morphine drug interactions.

What are the common drug interactions of Augmentin '250' and Morphine, by gender? *:

female:

Pneumonia
Protein urine
Rigors (an episode of shaking or exaggerated shivering)
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Transaminases increased
Tumour lysis syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)
Ureteric stenosis (abnormal narrowing or contraction of a duct or canal)
Diarrhoea

male:

Abdominal pain
Confusional state
Mucosal inflammation (infection of mucous membrane)
Muscle twitching
Nausea (feeling of having an urge to vomit)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Pulmonary embolism (blockage of the main artery of the lung)
Thrombocytopenia (decrease of platelets in blood)
Vomiting
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)

What are the common drug interactions of Augmentin '250' and Morphine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Anaemia (lack of blood)
Neck oedema (fluid collection in neck)
Oedema upper limb (swelling of arm)
Rash erythematous (redness of the skin)
Thrombocytopenia (decrease of platelets in blood)

40-49:

Anxiety
Feeling cold
Rigors (an episode of shaking or exaggerated shivering)

50-59:

Febrile neutropenia (fever with reduced white blood cells)
Diarrhoea
Anaemia (lack of blood)
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Blood albumin decreased
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
Renal haemorrhage (bleeding from kidney)
Stomatitis (inflammation of mucous membrane of mouth)
Troponin i increased

60+:

Abdominal pain
Blood amylase increased
Lipase increased
Mucosal inflammation (infection of mucous membrane)
Muscle twitching
Nausea (feeling of having an urge to vomit)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Pancreatitis acute (sudden inflammation of pancreas)
Pleural disorder
Pulmonary embolism (blockage of the main artery of the lung)

What are the existing conditions these people have? *

Stress And Anxiety: 7 people, 23.33%
Lung Disorder (lung disease): 6 people, 20.00%
Nausea (feeling of having an urge to vomit): 3 people, 10.00%
Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 3 people, 10.00%
Ankylosing Spondylitis (type of arthritis affecting the spine): 3 people, 10.00%
Psoriasis (immune-mediated disease that affects the skin): 2 people, 6.67%
High Blood Pressure: 2 people, 6.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 6.67%
Diarrhea: 2 people, 6.67%
Constipation: 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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