Augmentin and Caffeine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Augmentin (amoxicillin; clavulanate potassium) and Caffeine (caffeine). Common drug interactions include dizziness among females and maternal exposure before pregnancy among males.

The phase IV clinical study analyzes what interactions people have when they take Augmentin and Caffeine. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Augmentin?

Augmentin has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 42,620 Augmentin users. Check the latest studies of Augmentin.

What is Caffeine?

Caffeine has active ingredients of caffeine. It is often used in fatigue. eHealthMe is studying from 6,667 Caffeine users. Check the latest studies of Caffeine.

On Jul, 20, 2026

24 people who take Augmentin and Caffeine together, and have interactions are studied.

Augmentin and Caffeine drug interactions.

What are the common drug interactions of Augmentin and Caffeine, by gender? *:

female:

Dizziness
Dysentery (infection of the intestines resulting in severe diarrhoea with the presence of blood and mucus in the faeces)
Gait disturbance
Loss of consciousness
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Tongue paralysis (loss of function of tongue)
Vomiting
Drug hypersensitivity
Maternal exposure during pregnancy (use of substance during pregnancy)
Maternal exposure before pregnancy (use of substance before pregnancy)

male:

Maternal exposure before pregnancy (use of substance before pregnancy)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Foetal growth restriction (poor growth of a baby while in the mother's womb during pregnancy)
Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
Headache (pain in head)
Hordeolum (small collection of pus (abscess) on the eyelid)
Hypoxia (low oxygen in tissues)
Infusion related reaction
Infusion site pruritus (severe itching at infusion site)
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)

What are the common drug interactions of Augmentin and Caffeine, by age (0-1 to 60+)? *:

0-1:

Maternal exposure before pregnancy (use of substance before pregnancy)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Foetal growth restriction (poor growth of a baby while in the mother's womb during pregnancy)
Hypoxia (low oxygen in tissues)
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Respiratory distress (difficulty in breathing)

2-9:

n/a

10-19:

n/a

20-29:

Injury
Pain
Pulmonary embolism (blockage of the main artery of the lung)

30-39:

n/a

40-49:

Dizziness
Dysentery (infection of the intestines resulting in severe diarrhoea with the presence of blood and mucus in the faeces)
Gait disturbance
Loss of consciousness
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Tongue paralysis (loss of function of tongue)
Vomiting
Asthma
Autonomic neuropathy (malfunction of the autonomic nervous system (ans))
Back injury

50-59:

n/a

60+:

Headache (pain in head)
Hordeolum (small collection of pus (abscess) on the eyelid)
Chronic kidney disease
Disseminated tuberculosis
Drug hypersensitivity
Drug ineffective
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Pulmonary tuberculosis (lungs tuberculosis)
Tuberculosis of central nervous system (a bacterial infection of brain and spinal cord by mycobacterium tuberculosis)
Infusion related reaction

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 20.83%
Raynaud's Phenomenon (discoloration of the fingers, toes, and occasionally other areas): 3 people, 12.50%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 12.50%
Immunodeficiency Common Variable: 3 people, 12.50%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 12.50%
Skin Candida (fungal infection of skin): 2 people, 8.33%
Pneumonia: 2 people, 8.33%
Pain: 2 people, 8.33%
Nausea (feeling of having an urge to vomit): 2 people, 8.33%
Indigestion: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Augmentin and Caffeine?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously