Augmentin and Calan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Augmentin (amoxicillin; clavulanate potassium) and Calan (verapamil hydrochloride). Common drug interactions include peripheral vascular disorder among females and angina pectoris among males.

The phase IV clinical study analyzes what interactions people have when they take Augmentin and Calan. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Augmentin?

Augmentin has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 42,620 Augmentin users. Check the latest studies of Augmentin.

What is Calan?

Calan has active ingredients of verapamil hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 3,916 Calan users. Check the latest studies of Calan.

On Jul, 10, 2026

21 people who take Augmentin and Calan together, and have interactions are studied.

What are the common drug interactions of Augmentin and Calan, by gender? *:

female:

Peripheral vascular disorder
Sleep disorder
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
Upper respiratory tract infection
Weight increased
Abdominal pain upper
Acute respiratory distress syndrome
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Back pain

male:

Angina pectoris (chest pain due to ischemia of the heart muscle)
Anxiety
Depression
Essential hypertension (primary hypertension)
Fall
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Gout (uric acid crystals building up in the body)
Hepatic failure (liver failure)
Hepatitis (inflammation of the liver)
Humerus fracture (injury to the upper arm bone)

What are the common drug interactions of Augmentin and Calan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Chronic kidney disease
Renal failure (kidney dysfunction)

40-49:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chest pain
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Diabetes mellitus inadequate control
Diarrhoea
Headache (pain in head)
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Hepatitis (inflammation of the liver)
Liver fatty (fat deposition of liver)
Oedema lower limb (fluid collection in tissue of lower leg)

50-59:

Decreased activity
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Feeling cold
Gastroenteritis (inflammation of stomach and intestine)
Generalised oedema (swelling all over the body)
Heart rate irregular
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
Hepatic failure (liver failure)

60+:

Cardiac failure congestive
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Pneumonia
Renal failure acute (rapid kidney dysfunction)
Abdominal pain
Angina pectoris (chest pain due to ischemia of the heart muscle)
Anxiety
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)

What are the existing conditions these people have? *

Pain: 4 people, 19.05%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 9.52%
Fluid Retention (an abnormal accumulation of fluid in the blood): 2 people, 9.52%
Fever: 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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