Augmentin and Dolutegravir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Augmentin (amoxicillin; clavulanate potassium) and Dolutegravir (dolutegravir). Common drug interactions include nephrolithiasis among females and hyperkalaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Augmentin and Dolutegravir. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Augmentin?

Augmentin has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 42,620 Augmentin users. Check the latest studies of Augmentin.

What is Dolutegravir?

Dolutegravir has active ingredients of dolutegravir. eHealthMe is studying from 7,071 Dolutegravir users. Check the latest studies of Dolutegravir.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

27 people who take Augmentin and Dolutegravir together, and have interactions are studied.

Augmentin and Dolutegravir drug interactions.

What are the common drug interactions of Augmentin and Dolutegravir, by gender? *:

female:

Nephrolithiasis (calculi in the kidneys)
Abortion spontaneous (naturally occurring miscarriage)
Renal failure (kidney dysfunction)

male:

Hyperkalaemia (damage to or disease of the kidney)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Mixed liver injury
Pain
Renal impairment (severely reduced kidney function)
Respiratory failure (inadequate gas exchange by the respiratory system)
Bone density decreased
Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
Drug ineffective
Dyspnoea (difficult or laboured respiration)

What are the common drug interactions of Augmentin and Dolutegravir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Nephrolithiasis (calculi in the kidneys)

20-29:

Abortion spontaneous (naturally occurring miscarriage)

30-39:

Renal failure (kidney dysfunction)

40-49:

Abortion spontaneous (naturally occurring miscarriage)
Diarrhoea
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Respiratory failure (inadequate gas exchange by the respiratory system)
Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
Drug ineffective
Dyspnoea (difficult or laboured respiration)
Gastroenteritis cryptosporidial (inflammation of stomach and intestine caused by cryptosporidial infection)
General physical health deterioration (weak health status)
Hypotonia (low muscle tone)

50-59:

Hyperkalaemia (damage to or disease of the kidney)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Renal impairment (severely reduced kidney function)
Bone density decreased
Eosinophilia (eosinophil count in the peripheral blood exceeds)
Foot fracture
Multiple fractures
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Tibia fracture (fracture of lower leg bone)

60+:

n/a

What are the existing conditions these people have? *

Hiv Infection: 14 people, 51.85%
Lung Disorder (lung disease): 4 people, 14.81%
Infection: 4 people, 14.81%
Diarrhea: 4 people, 14.81%
Affective Disorder (mental disorder): 3 people, 11.11%
Pneumonia Pneumococcal (pneumococcal pneumonia is a common but serious infection and inflammation of the lungs): 2 people, 7.41%
Folliculitis (infection of hair root): 2 people, 7.41%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 2 people, 7.41%
Dry Skin: 2 people, 7.41%
Cheilitis (infection of lips): 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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