Augmentin and Duricef drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Augmentin (amoxicillin; clavulanate potassium) and Duricef (cefadroxil/cefadroxil hemihydrate). Common drug interactions include drug hypersensitivity among females and cellulitis among males.
The phase IV clinical study analyzes what interactions people have when they take Augmentin and Duricef. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.
What is Augmentin?
Augmentin has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 42,620 Augmentin users. Check the latest studies of Augmentin.
What is Duricef?
Duricef has active ingredients of cefadroxil/cefadroxil hemihydrate. eHealthMe is studying from 579 Duricef users. Check the latest studies of Duricef.
16 people who take Augmentin and Duricef together, and have interactions are studied.

What are the common drug interactions of Augmentin and Duricef, by gender? *:
female:
- Drug hypersensitivity
- Acute pulmonary oedema (sudden deposit of fluid in the lung))
- Anaemia (lack of blood)
- Anaemia postoperative
- Angina pectoris (chest pain due to ischemia of the heart muscle)
- Anxiety
- Blood creatinine increased
- Carbon dioxide increased
- Cardiac failure congestive
- Cerebral infarction (less blood supply to brain resulting tissue damage)
male:
- Cellulitis (infection under the skin)
- Postoperative wound complication
- Drug level increased
- Dysuria (painful or difficult urination)
- Enterobiasis (intestinal infection caused by the parasitic roundworm called enterobius vermicularis)
- Headache (pain in head)
- Malaise (a feeling of general discomfort or uneasiness)
- Otitis externa (external ear infection)
- Otitis media (inflammation of the middle ear)
- Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
What are the common drug interactions of Augmentin and Duricef, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Arrhythmia (irregular heartbeat)
- Sudden death
- Unresponsive to stimuli
- Vomiting
- Abdominal pain
- Drug level increased
- Dysuria (painful or difficult urination)
- Enterobiasis (intestinal infection caused by the parasitic roundworm called enterobius vermicularis)
- Headache (pain in head)
- Hyperhidrosis (abnormally increased sweating)
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Anaemia postoperative
- Angina pectoris (chest pain due to ischemia of the heart muscle)
- Cerebral infarction (less blood supply to brain resulting tissue damage)
- Cerebrovascular disorder (disease of brain)
- Chest pain
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Haematuria (presence of blood in urine)
- Herpes simplex (herpes simplex is a common viral infection)
- Hyperlipidaemia (presence of excess lipids in the blood)
- Obesity (having too much body fat)
50-59:
- Arthralgia (joint pain)
- Drug hypersensitivity
- Hyperhidrosis (abnormally increased sweating)
- Inflammation
- Productive cough
- Serum sickness (hypersensitivity reaction that results from the injection of heterologous or foreign protein or serum)
- Skin exfoliation (removal of the oldest dead skin cells)
60+:
- Cellulitis (infection under the skin)
- Hypotension (abnormally low blood pressure)
- Depression
- Drug hypersensitivity
- Dyspnoea (difficult or laboured respiration)
- Dyspnoea exertional (breathlessness or shortness of breath)
- Electrolyte imbalance
- Fluid overload (too much fluid in the blood)
- Fluid retention (an abnormal accumulation of fluid in the blood)
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
What are the existing conditions these people have? *
- High Blood Pressure: 5 people, 31.25%
- Thrombosis (formation of a blood clot inside a blood vessel): 3 people, 18.75%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 3 people, 18.75%
- Prostate Cancer: 3 people, 18.75%
- Diabetes: 3 people, 18.75%
- Dyspnea (difficult or laboured breathing): 3 people, 18.75%
- Oropharyngeal Pain: 3 people, 18.75%
- High Density Lipoprotein Decreased: 3 people, 18.75%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 12.50%
- Depression: 2 people, 12.50%
* Approximation only. Some reports may have incomplete information.
Do you take Augmentin and Duricef?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Augmentin and Duricef:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Augmentin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Duricef:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Augmentin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Duricef and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on amoxicillin; clavulanate potassium and cefadroxil/cefadroxil hemihydrate (the active ingredients of Augmentin and Duricef, respectively), and Augmentin and Duricef (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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