Astepro and Dulcolax drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Astepro (azelastine hydrochloride) and Dulcolax (bisacodyl). Common drug interactions include decreased appetite among females and hyponatraemia among males.

The phase IV clinical study analyzes what interactions people have when they take Astepro and Dulcolax. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Astepro?

Astepro has active ingredients of azelastine hydrochloride. It is often used in allergies. eHealthMe is studying from 3,336 Astepro users. Check the latest studies of Astepro.

What is Dulcolax?

Dulcolax has active ingredients of bisacodyl. It is often used in constipation. eHealthMe is studying from 12,897 Dulcolax users. Check the latest studies of Dulcolax.



On Jul, 13, 2026

13 people who take Astepro and Dulcolax together, and have interactions are studied.

Astepro and Dulcolax drug interactions.

What are the common drug interactions of Astepro and Dulcolax, by gender? *:

female:

  1. Decreased appetite
  2. Infection
  3. Headache (pain in head)
  4. Hearing disability
  5. Influenza
  6. Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
  7. Neck pain
  8. Pneumonia
  9. Rhinorrhoea (watery mucus discharge from the nose)
  10. Asthenia (weakness)

male:

  1. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  2. Urinary tract infection
  3. Confusional state
  4. Decreased appetite
  5. Dehydration (dryness resulting from the removal of water)
  6. Disease progression
  7. Fatigue (feeling of tiredness)
  8. Flatulence (flatus expelled through the anus)
  9. Gait disturbance
  10. Gastric haemorrhage (bleeding stomach)

What are the common drug interactions of Astepro and Dulcolax, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Decreased appetite
  2. Infection
  3. Pneumonia
  4. Rhinorrhoea (watery mucus discharge from the nose)
  5. Anaemia (lack of blood)
  6. Arthralgia (joint pain)
  7. Back pain
  8. Blood glucose fluctuation
  9. Bradycardia (abnormally slow heart action)
  10. Cardiac failure congestive

What are the existing conditions these people have? *

  1. Antiphospholipid Syndrome (disorder that manifests clinically as recurrent venous or arterial thrombosis and/or fetal loss): 4 people, 30.77%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 30.77%
  3. Pain: 4 people, 30.77%
  4. Basedow's Disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones): 4 people, 30.77%
  5. Migraine (headache): 4 people, 30.77%
  6. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 4 people, 30.77%
  7. Chronic Thyroiditis (long lasting inflammation of thyroid gland): 4 people, 30.77%
  8. Asthma: 2 people, 15.38%
  9. Bladder Cancer: 2 people, 15.38%
  10. Nausea (feeling of having an urge to vomit): 2 people, 15.38%

* Approximation only. Some reports may have incomplete information.

Do you take Astepro and Dulcolax?

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- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Astepro and Dulcolax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Astepro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Dulcolax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Astepro and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Dulcolax and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on azelastine hydrochloride and bisacodyl (the active ingredients of Astepro and Dulcolax, respectively), and Astepro and Dulcolax (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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