Folate and Cozaar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Folate (folic acid) and Cozaar (losartan potassium). Common drug interactions include constipation among females and gout among males.

The phase IV clinical study analyzes what interactions people have when they take Folate and Cozaar. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Folate?

Folate has active ingredients of folic acid. It is often used in rheumatoid arthritis. eHealthMe is studying from 6,546 Folate users. Check the latest studies of Folate.

What is Cozaar?

Cozaar has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 45,124 Cozaar users. Check the latest studies of Cozaar.



On Jul, 13, 2026

42 people who take Folate and Cozaar together, and have interactions are studied.

Folate and Cozaar drug interactions.

What are the common drug interactions of Folate and Cozaar, by gender? *:

female:

  1. Constipation
  2. Decreased appetite
  3. Insomnia (sleeplessness)
  4. Pneumonia
  5. Abdominal pain upper
  6. Anaemia (lack of blood)
  7. Angioedema (rapid swelling of the dermis)
  8. Carotid artery disease
  9. Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
  10. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

male:

  1. Gout (uric acid crystals building up in the body)
  2. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  3. Fatigue (feeling of tiredness)
  4. Headache (pain in head)
  5. Hyperlipidaemia (presence of excess lipids in the blood)
  6. Mitral valve incompetence (inefficient heart valve)
  7. Pneumonia
  8. Renal failure (kidney dysfunction)
  9. Upper respiratory tract infection
  10. Abdominal pain

What are the common drug interactions of Folate and Cozaar, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Death
  2. Fatigue (feeling of tiredness)
  3. Malignant pleural effusion (a condition in which cancer causes an abnormal amount of fluid to collect between the thin layers of tissue lining of lung)
  4. Metastases to kidney (cancer spreads to kidney)
  5. Muscular weakness (muscle weakness)
  6. Proteinuria (presence of protein in the urine)
  7. Wheezing (a high-pitched whistling sound made while you breath)

50-59:

  1. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  2. Multi-organ failure (multisystem organ failure)
  3. Pain
  4. Renal failure (kidney dysfunction)
  5. Blood amylase increased
  6. Chronic kidney disease
  7. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  8. Conjunctivitis (pink eye)
  9. Decreased appetite
  10. Drug dependence

60+:

  1. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  2. Renal failure (kidney dysfunction)
  3. Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
  4. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  5. Constipation
  6. Haemoglobin decreased
  7. Hypoxia (low oxygen in tissues)
  8. Ischaemic cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease)
  9. Pneumonia
  10. Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 9 people, 21.43%
  2. Non-Small Cell Lung Cancer Metastatic (type of epithelial lung cancer spreads to other parts): 4 people, 9.52%
  3. Insomnia (sleeplessness): 3 people, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Folate and Cozaar?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Folate and Cozaar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Folate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cozaar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Folate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cozaar and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on folic acid and losartan potassium (the active ingredients of Folate and Cozaar, respectively), and Folate and Cozaar (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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