Augmentin and Loperamide hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Augmentin (amoxicillin; clavulanate potassium) and Loperamide hydrochloride (loperamide hydrochloride). Common drug interactions include emotional distress among females and thrombocytopenia among males.

The phase IV clinical study analyzes what interactions people have when they take Augmentin and Loperamide hydrochloride. It is created by eHealthMe based on reports of 65 people who take the same drugs from the FDA, and is updated regularly.

What is Augmentin?

Augmentin has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 42,620 Augmentin users. Check the latest studies of Augmentin.

What is Loperamide hydrochloride?

Loperamide hydrochloride has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 10,814 Loperamide hydrochloride users. Check the latest studies of Loperamide hydrochloride.

On Jul, 17, 2026

65 people who take Augmentin and Loperamide hydrochloride together, and have interactions are studied.

Augmentin and Loperamide hydrochloride drug interactions.

What are the common drug interactions of Augmentin and Loperamide Hydrochloride, by gender? *:

female:

Emotional distress
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
Exophthalmos (bulging or protruding eyeball)
Exposed bone in jaw
Fatigue (feeling of tiredness)
Gamma-glutamyltransferase increased
Gingival disorder (gum disease)
Gingivitis (inflammation of gums)
Haematuria (presence of blood in urine)
Hallucination (an experience involving the perception of something not present)

male:

Thrombocytopenia (decrease of platelets in blood)
Leukopenia (less number of white blood cells in blood)
Hand fracture
Oedema (fluid collection in tissue)
Pertussis (whooping cough: a disease of the respiratory mucous membrane)
Polyarthritis (arthritis which involves 5 or more joints simultaneously)
Puncture site pain
Pyoderma gangrenosum (ulcerating condition of skin that results in heaped borders with a typical appearance)
Skin erosion (a discontinuity of the skin)
Stomatitis (inflammation of mucous membrane of mouth)

What are the common drug interactions of Augmentin and Loperamide Hydrochloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
Device occlusion
Drug chemical incompatibility
Blood iron decreased
Cyst (a closed sac)
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Fall
Fungal infection
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Headache (pain in head)

40-49:

Femoral neck fracture (neck of femur bone fracture)
Insomnia (sleeplessness)
Pertussis (whooping cough: a disease of the respiratory mucous membrane)
Polyarthritis (arthritis which involves 5 or more joints simultaneously)
Stomatitis (inflammation of mucous membrane of mouth)
Urge incontinence (urinary incontinence)
Eosinophilic pneumonia (eosinophil accumulates in the lung)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Activities of daily living impaired
Adenocarcinoma (malignant tumour formed from glandular structures in epithelial tissue)

50-59:

Gait disturbance
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Gingival disorder (gum disease)
Hypoaesthesia (reduced sense of touch or sensation)
Jaw fracture
Multiple myeloma (cancer of the plasma cells)
Muscular weakness (muscle weakness)
Nausea (feeling of having an urge to vomit)
Neck pain
Night sweats (sweating in night)

60+:

Thrombocytopenia (decrease of platelets in blood)
Leukopenia (less number of white blood cells in blood)
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Anaemia (lack of blood)
Bone marrow depression (decreased ability or inability of the bone marrow to produce blood cells)
Cardiac failure congestive
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dehydration (dryness resulting from the removal of water)
Depressed level of consciousness

What are the existing conditions these people have? *

Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 9 people, 13.85%
High Blood Pressure: 6 people, 9.23%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 6 people, 9.23%
Urinary Tract Infection: 5 people, 7.69%
High Blood Cholesterol: 5 people, 7.69%
Stomatitis (inflammation of mucous membrane of mouth): 4 people, 6.15%
Nausea (feeling of having an urge to vomit): 4 people, 6.15%
Headache (pain in head): 4 people, 6.15%
Diabetes: 4 people, 6.15%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 4 people, 6.15%

* Approximation only. Some reports may have incomplete information.

Do you take Augmentin and Loperamide hydrochloride?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously