Augmentin and Plendil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Augmentin (amoxicillin; clavulanate potassium) and Plendil (felodipine). Common drug interactions include abdominal distension among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Augmentin and Plendil. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Augmentin?

Augmentin has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 42,620 Augmentin users. Check the latest studies of Augmentin.

What is Plendil?

Plendil has active ingredients of felodipine. It is often used in high blood pressure. eHealthMe is studying from 4,990 Plendil users. Check the latest studies of Plendil.

On Jul, 23, 2026

18 people who take Augmentin and Plendil together, and have interactions are studied.

Augmentin and Plendil drug interactions.

What are the common drug interactions of Augmentin and Plendil, by gender? *:

female:

Abdominal distension
Acute myocardial infarction (acute heart attack)
Arthralgia (joint pain)
Asthenia (weakness)
Atrioventricular block complete (heart block complete)
Balance disorder
Buttock pain
Carotid artery occlusion (artery blockage)
Carotid artery stenosis (narrowing of carotid artery)
Dizziness

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Hepatitis cholestatic (flow of bile from the liver is slowed or blocked)
Injection site dermatitis
Injection site erythema (redness at injection site)
Injection site urticaria (rash of round, red welts on the skin at injection site)
Insomnia (sleeplessness)
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Jaundice cholestatic
Lung neoplasm malignant (cancer tumour of lung)

What are the common drug interactions of Augmentin and Plendil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Chronic kidney disease
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Depression
Suicidal ideation

40-49:

n/a

50-59:

Hepatitis (inflammation of the liver)
Hepatitis cholestatic (flow of bile from the liver is slowed or blocked)
Injection site dermatitis
Injection site erythema (redness at injection site)
Injection site urticaria (rash of round, red welts on the skin at injection site)
Insomnia (sleeplessness)
Jaundice cholestatic

60+:

Abdominal distension
Acute myocardial infarction (acute heart attack)
Dizziness
Dizziness postural
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Mitral valve incompetence (inefficient heart valve)
Peripheral vascular disorder
Sick sinus syndrome (a collection of heart rhythm disorders)
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))

What are the existing conditions these people have? *

Asthma: 5 people, 27.78%
Diabetes: 5 people, 27.78%
Vasodilatation (widening of blood vessels resulting from relaxation of smooth muscle cells within the vessel walls): 3 people, 16.67%
High Blood Cholesterol: 3 people, 16.67%
Bacterial Infection: 3 people, 16.67%
Blood Calcium Decreased: 3 people, 16.67%
Blood Glucose Fluctuation: 3 people, 16.67%
Blood Testosterone Abnormal: 3 people, 16.67%
Chest Pain: 3 people, 16.67%
Fluid Retention (an abnormal accumulation of fluid in the blood): 3 people, 16.67%

* Approximation only. Some reports may have incomplete information.

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