Trulicity and Hetlioz drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Trulicity (dulaglutide) and Hetlioz (tasimelteon). Common drug interactions include drug ineffective among females and insomnia among males.
The phase IV clinical study analyzes what interactions people have when they take Trulicity and Hetlioz. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.
What is Trulicity?
Trulicity has active ingredients of dulaglutide. It is often used in weight loss. eHealthMe is studying from 77,529 Trulicity users. Check the latest studies of Trulicity.
What is Hetlioz?
Hetlioz has active ingredients of tasimelteon. eHealthMe is studying from 7,418 Hetlioz users. Check the latest studies of Hetlioz.
38 people who take Trulicity and Hetlioz together, and have interactions are studied.

What are the common drug interactions of Trulicity and Hetlioz, by gender? *:
female:
- Drug ineffective
- Insomnia (sleeplessness)
- Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
- Bacterial infection
- Dehydration (dryness resulting from the removal of water)
- Renal failure (kidney dysfunction)
- Pain
- Poor quality sleep
- Chapped lips (cracking, fissuring, and peeling of the skin f lip)
- Conjunctivitis (pink eye)
male:
- Insomnia (sleeplessness)
- Headache (pain in head)
- Constipation
- Decreased activity
- Drug ineffective
- Eating disorder
- Migraine (headache)
- Poor quality sleep
- Sinus congestion (blockage of sinus)
- Sinusitis (inflammation of sinus)
What are the common drug interactions of Trulicity and Hetlioz, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Drug ineffective
- Hypersomnia (excessive daytime sleepiness (eds))
40-49:
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Adverse drug reaction
- Circadian rhythm sleep disorder (family of sleep disorders affecting, among other things, the timing of sleep)
- Constipation
- Decreased activity
- Eating disorder
- Insomnia (sleeplessness)
- Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
- Stress
50-59:
- Headache (pain in head)
- Migraine (headache)
- Sinus congestion (blockage of sinus)
- Sinusitis (inflammation of sinus)
60+:
- Bacterial infection
- Chapped lips (cracking, fissuring, and peeling of the skin f lip)
- Anxiety
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Dehydration (dryness resulting from the removal of water)
- Dizziness
- Drug ineffective
- Fall
- Insomnia (sleeplessness)
- Memory impairment
What are the existing conditions these people have? *
- Circadian Rhythm Sleep Disorder (family of sleep disorders affecting, among other things, the timing of sleep): 8 people, 21.05%
- Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 2 people, 5.26%
* Approximation only. Some reports may have incomplete information.
Do you take Trulicity and Hetlioz?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Trulicity and Hetlioz:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Trulicity:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Hetlioz:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Trulicity and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Hetlioz and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on dulaglutide and tasimelteon (the active ingredients of Trulicity and Hetlioz, respectively), and Trulicity and Hetlioz (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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