Austedo and Spironolactone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Austedo (deutetrabenazine) and Spironolactone (spironolactone). Common drug interactions include transient ischaemic attack among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Austedo and Spironolactone. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Austedo?

Austedo has active ingredients of deutetrabenazine. eHealthMe is studying from 4,141 Austedo users. Check the latest studies of Austedo.

What is Spironolactone?

Spironolactone has active ingredients of spironolactone. It is often used in acne. eHealthMe is studying from 122,947 Spironolactone users. Check the latest studies of Spironolactone.

On Jul, 12, 2026

18 people who take Austedo and Spironolactone together, and have interactions are studied.

Austedo and Spironolactone drug interactions.

What are the common drug interactions of Austedo and Spironolactone, by gender? *:

female:

Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
Weight decreased
Cardiac disorder
Coma (state of unconsciousness lasting more than six hours)
Cough
Pneumonia
Sepsis (a severe blood infection that can lead to organ failure and death)
Ulcer
Adverse event
Blood pressure decreased

male:

Drug ineffective
Nausea (feeling of having an urge to vomit)
Overdose
Reaction to colouring
Vomiting

What are the common drug interactions of Austedo and Spironolactone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Depression
Suicidal ideation

50-59:

Nausea (feeling of having an urge to vomit)
Overdose
Reaction to colouring
Vomiting

60+:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Somnambulism (sleep walking)
Sepsis (a severe blood infection that can lead to organ failure and death)
Ulcer
Adverse event
Blood pressure decreased
Bone pain
Chills (felling of cold)
Confusional state
Depression

What are the existing conditions these people have? *

Tardive Dyskinesia (a disorder that involves involuntary movements): 10 people, 55.56%
Parkinson's Disease: 2 people, 11.11%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 11.11%
Drowsiness: 2 people, 11.11%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 11.11%
Hereditary Angioedema (recurrent episodes of severe swelling): 1 person, 5.56%
Hallucinations (sensations that appear real but are created by your mind): 1 person, 5.56%
Dyskinesia (abnormality or impairment of voluntary movement): 1 person, 5.56%
Delusion (a false belief or opinion): 1 person, 5.56%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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