Avalide and Atorvastatin calcium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Avalide (hydrochlorothiazide; irbesartan) and Atorvastatin calcium (atorvastatin calcium). Common drug interactions include renal failure among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Avalide and Atorvastatin calcium. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Avalide?

Avalide has active ingredients of hydrochlorothiazide; irbesartan. It is often used in high blood pressure. eHealthMe is studying from 5,943 Avalide users. Check the latest studies of Avalide.

What is Atorvastatin calcium?

Atorvastatin calcium has active ingredients of atorvastatin calcium. It is often used in high blood cholesterol. eHealthMe is studying from 77,309 Atorvastatin calcium users. Check the latest studies of Atorvastatin calcium.

On Jul, 17, 2026

28 people who take Avalide and Atorvastatin calcium together, and have interactions are studied.

Avalide and Atorvastatin calcium drug interactions.

What are the common drug interactions of Avalide and Atorvastatin Calcium, by gender? *:

female:

Renal failure (kidney dysfunction)
Cyst (a closed sac)
Diarrhoea
Muscle spasms (muscle contraction)
Neuropathy peripheral (surface nerve damage)
Restless legs syndrome (a powerful urge to move your legs)
Rheumatoid nodule (a local swelling or tissue lump with rheumatoid disease)
Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)

male:

Chronic kidney disease
Cardiac failure congestive
Asthenia (weakness)
Dry mouth
Erectile dysfunction
Fall
Heart rate increased
Hypotonia (low muscle tone)
Injury
Insomnia (sleeplessness)

What are the common drug interactions of Avalide and Atorvastatin Calcium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Chronic kidney disease

20-29:

n/a

30-39:

n/a

40-49:

Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)

50-59:

Fall
Alopecia (absence of hair from areas of the body)
Deformity (disfigurement)
Nerve injury
Scar
Skin exfoliation (removal of the oldest dead skin cells)
Ulcer
Asthenia (weakness)
Cardiac failure congestive
Dysgeusia (disorder of the sense of taste)

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Heart rate increased
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Injection site pain
Insomnia (sleeplessness)
Interstitial lung disease
Pancreatitis acute (sudden inflammation of pancreas)
Pericardial effusion (fluid around the heart)

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 8 people, 28.57%
Diabetes: 6 people, 21.43%
Pain: 4 people, 14.29%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 14.29%
Depression: 3 people, 10.71%
Hypersensitivity: 3 people, 10.71%
Multiple Myeloma (cancer of the plasma cells): 3 people, 10.71%
Insomnia (sleeplessness): 3 people, 10.71%
Constipation: 2 people, 7.14%
Chest Pain: 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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