Avalide and Augmentin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Avalide (hydrochlorothiazide; irbesartan) and Augmentin (amoxicillin; clavulanate potassium). Common drug interactions include decreased appetite among females and atrial fibrillation among males.

The phase IV clinical study analyzes what interactions people have when they take Avalide and Augmentin. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Avalide?

Avalide has active ingredients of hydrochlorothiazide; irbesartan. It is often used in high blood pressure. eHealthMe is studying from 5,943 Avalide users. Check the latest studies of Avalide.

What is Augmentin?

Augmentin has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 42,620 Augmentin users. Check the latest studies of Augmentin.

On Jul, 11, 2026

33 people who take Avalide and Augmentin together, and have interactions are studied.

Avalide and Augmentin drug interactions.

What are the common drug interactions of Avalide and Augmentin, by gender? *:

female:

Decreased appetite
Fatigue (feeling of tiredness)
Hypoaesthesia (reduced sense of touch or sensation)
Impaired healing
Insomnia (sleeplessness)
Lower limb fracture
Pain in extremity
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
Breast discharge
Deformity (disfigurement)

male:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Aortic valve incompetence
Arthralgia (joint pain)
Bacterial infection
Blepharospasm (any abnormal contraction or twitch of the eyelid)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
Breast cancer
Breast discharge

What are the common drug interactions of Avalide and Augmentin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Anaemia (lack of blood)
Aortic arteriosclerosis (hardening of the aortic arteries)
Aortic valve incompetence
Arthralgia (joint pain)
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
Breast cancer
Breast discharge
Breast hyperplasia (accumulation of abnormal cells in a breast duct)
Breast mass

40-49:

Dysgeusia (disorder of the sense of taste)
Hyposmia (impairment of the sense of smell)

50-59:

Thyroid mass
Gait disturbance
Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly)
Aortic arteriosclerosis (hardening of the aortic arteries)
Aortic valve incompetence
Breast cancer
Breast hyperplasia (accumulation of abnormal cells in a breast duct)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)

60+:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Arthralgia (joint pain)
Arthropathy
Back pain
Bacterial infection
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac failure congestive
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Cardioactive drug level increased
Chronic kidney disease

What are the existing conditions these people have? *

Diabetes: 10 people, 30.30%
Multiple Myeloma (cancer of the plasma cells): 9 people, 27.27%
High Blood Cholesterol: 5 people, 15.15%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 15.15%
Hepatitis C: 3 people, 9.09%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 9.09%
Upper Respiratory Tract Infection: 2 people, 6.06%
Pain: 2 people, 6.06%
Nausea (feeling of having an urge to vomit): 2 people, 6.06%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 6.06%

* Approximation only. Some reports may have incomplete information.

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