Avalide and Claritin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Avalide (hydrochlorothiazide; irbesartan) and Claritin (loratadine). Common drug interactions include gastric ulcer among females and headache among males.

The phase IV clinical study analyzes what interactions people have when they take Avalide and Claritin. It is created by eHealthMe based on reports of 75 people who take the same drugs from the FDA, and is updated regularly.

What is Avalide?

Avalide has active ingredients of hydrochlorothiazide; irbesartan. It is often used in high blood pressure. eHealthMe is studying from 5,943 Avalide users. Check the latest studies of Avalide.

What is Claritin?

Claritin has active ingredients of loratadine. It is often used in allergies. eHealthMe is studying from 77,315 Claritin users. Check the latest studies of Claritin.

On Jul, 27, 2026

75 people who take Avalide and Claritin together, and have interactions are studied.

What are the common drug interactions of Avalide and Claritin, by gender? *:

female:

Gastric ulcer (stomach ulcer)
Dyspnoea (difficult or laboured respiration)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Contusion (a type of hematoma of tissue in which capillaries)
Patellofemoral pain syndrome (pain in the front of the knee)
Therapeutic response decreased (less preventive response)
Cellulitis (infection under the skin)
Chondromalacia (anterior knee pain due to irritation of the cartilage on the under surface of the kneecap)
Chest pain
Fatigue (feeling of tiredness)

male:

Headache (pain in head)
Fatigue (feeling of tiredness)
Hyperhidrosis (abnormally increased sweating)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Dyspepsia (indigestion)
Diarrhoea
Abdominal discomfort
Arthralgia (joint pain)
Cardiac failure congestive
Dizziness

What are the common drug interactions of Avalide and Claritin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Asthma
Anaemia (lack of blood)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Aortic valve incompetence
Asthenia (weakness)
Bronchitis acute (acute inflammation of the mucous membrane in the bronchial tubes)
Chest pain
Decreased appetite
Depression

40-49:

Anxiety
Dyspepsia (indigestion)
Headache (pain in head)
Intervertebral disc degeneration (spinal disc degeneration)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Anaemia (lack of blood)
Arthralgia (joint pain)
Back pain
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

50-59:

Gastric ulcer (stomach ulcer)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Nausea (feeling of having an urge to vomit)
Contusion (a type of hematoma of tissue in which capillaries)
Patellofemoral pain syndrome (pain in the front of the knee)
Therapeutic response decreased (less preventive response)
Headache (pain in head)
Abdominal pain
Anaemia (lack of blood)
Cellulitis (infection under the skin)

60+:

Diarrhoea
Renal failure (kidney dysfunction)
Urinary tract infection
Abdominal distension
Anxiety
Arthralgia (joint pain)
Back pain
Bone disorder
Cardiac failure congestive
Cardiogenic shock (inadequate circulation of blood)

What are the existing conditions these people have? *

Arthritis (form of joint disorder that involves inflammation of one or more joints): 11 people, 14.67%
Urinary Tract Infection: 9 people, 12.00%
Pain: 8 people, 10.67%
Sinusitis (inflammation of sinus): 4 people, 5.33%
Multiple Allergies (allergy to multiple agents): 4 people, 5.33%
High Blood Cholesterol: 4 people, 5.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 5.33%
Asthma: 4 people, 5.33%

* Approximation only. Some reports may have incomplete information.

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