Frova and Norvasc drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Frova (frovatriptan succinate) and Norvasc (amlodipine besylate). Common drug interactions include arthralgia among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Frova and Norvasc. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Frova?

Frova has active ingredients of frovatriptan succinate. It is often used in migraine. eHealthMe is studying from 2,100 Frova users. Check the latest studies of Frova.

What is Norvasc?

Norvasc has active ingredients of amlodipine besylate. It is often used in high blood pressure. eHealthMe is studying from 136,738 Norvasc users. Check the latest studies of Norvasc.

On Jul, 27, 2026

18 people who take Frova and Norvasc together, and have interactions are studied.

What are the common drug interactions of Frova and Norvasc, by gender? *:

female:

Arthralgia (joint pain)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Pulmonary embolism (blockage of the main artery of the lung)
Sinusitis (inflammation of sinus)
Weight increased
Neuropathy peripheral (surface nerve damage)
Activities of daily living impaired
Alanine aminotransferase increased

male:

Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)
Secondary hyperthyroidism

What are the common drug interactions of Frova and Norvasc, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)
Injury
Pain
Pulmonary embolism (blockage of the main artery of the lung)

30-39:

n/a

40-49:

Cough
Euphoric mood (excessively happy but may become angry or irritable)
Increased upper airway secretion
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)

50-59:

Toothache (tooth pain)
Tremor (trembling or shaking movements in one or more parts of your body)
Upper respiratory tract infection
Ventricular extrasystoles (premature cardiac contraction)
Vitamin d decreased
Vomiting
White blood cell count increased
Abdominal pain upper
Activities of daily living impaired
Alanine aminotransferase increased

60+:

Neuropathy peripheral (surface nerve damage)
Abdominal pain upper
Oral infection
Pain
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)
Secondary hyperthyroidism
Sinusitis (inflammation of sinus)
Tenderness (pain or discomfort when an affected area is touched)
Tooth disorder (tooth disease)

What are the existing conditions these people have? *

Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 3 people, 16.67%
Birth Control: 2 people, 11.11%
Stress And Anxiety: 1 person, 5.56%
Headache (pain in head): 1 person, 5.56%
Bipolar Disorder (mood disorder): 1 person, 5.56%
Breast Cancer: 1 person, 5.56%
Depression: 1 person, 5.56%
Essential Hypertension (primary hypertension): 1 person, 5.56%
Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 5.56%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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