Avandia and Trimox drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Avandia (rosiglitazone maleate) and Trimox (amoxicillin). Common drug interactions include adverse event among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Avandia and Trimox. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Avandia?

Avandia has active ingredients of rosiglitazone maleate. It is often used in diabetes. eHealthMe is studying from 142,155 Avandia users. Check the latest studies of Avandia.

What is Trimox?

Trimox has active ingredients of amoxicillin. eHealthMe is studying from 932 Trimox users. Check the latest studies of Trimox.



On Aug, 01, 2026

25 people who take Avandia and Trimox together, and have interactions are studied.

Avandia and Trimox drug interactions.

What are the common drug interactions of Avandia and Trimox, by gender? *:

female:

  1. Adverse event
  2. Chronic kidney disease
  3. Hepatic steatosis (fatty liver disease)
  4. Renal failure (kidney dysfunction)

male:

  1. Pain
  2. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  3. Cardiac failure congestive
  4. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  5. Diarrhoea
  6. Emotional distress
  7. Fatigue (feeling of tiredness)
  8. Hyperhidrosis (abnormally increased sweating)
  9. Hypokalaemia (low potassium)
  10. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)

What are the common drug interactions of Avandia and Trimox, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Cardiomegaly (increased size of heart than normal)
  2. Dyspepsia (indigestion)
  3. Dyspnoea (difficult or laboured respiration)
  4. Ear infection
  5. Flushing (the warm, red condition of human skin)
  6. Joint sprain (an injury to joint surrounding flexible fibres)
  7. Lipoma (a growth of fatty tissue that slowly develops just under your skin)
  8. Malignant histiocytosis (cancerous increase in the number of immune cells)
  9. Pruritus (severe itching of the skin)
  10. Renal disorder (kidney disease)

50-59:

  1. Hepatocellular damage (liver damage)
  2. High density lipoprotein decreased
  3. Hypocholesterolaemia (presence of abnormally small amounts of cholesterol in the circulating blood)
  4. Impaired gastric emptying
  5. Ingrowing nail
  6. Lacrimation increased
  7. Pain in limb
  8. Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)
  9. Sensation of foreign body
  10. Syncope (loss of consciousness with an inability to maintain postural tone)

60+:

  1. Pain
  2. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  3. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  4. Diabetes mellitus inadequate control
  5. Diarrhoea
  6. Emotional distress
  7. Fatigue (feeling of tiredness)
  8. Hyperhidrosis (abnormally increased sweating)
  9. Hypokalaemia (low potassium)
  10. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)

What are the existing conditions these people have? *

  1. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 20.00%
  2. Idiopathic Pulmonary Fibrosis (chronic lung disease): 3 people, 12.00%
  3. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 3 people, 12.00%
  4. Inflammation: 2 people, 8.00%
  5. Cardiac Disorder: 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

Do you take Avandia and Trimox?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Avandia and Trimox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Avandia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Trimox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Avandia and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Trimox and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on rosiglitazone maleate and amoxicillin (the active ingredients of Avandia and Trimox, respectively), and Avandia and Trimox (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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