Avelox and Linzess drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Avelox (moxifloxacin hydrochloride) and Linzess (linaclotide). Common drug interactions include chronic kidney disease among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Avelox and Linzess. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Avelox?

Avelox has active ingredients of moxifloxacin hydrochloride. It is often used in sinusitis. eHealthMe is studying from 28,651 Avelox users. Check the latest studies of Avelox.

What is Linzess?

Linzess has active ingredients of linaclotide. It is often used in constipation. eHealthMe is studying from 24,086 Linzess users. Check the latest studies of Linzess.

On Jul, 18, 2026

17 people who take Avelox and Linzess together, and have interactions are studied.

What are the common drug interactions of Avelox and Linzess, by gender? *:

female:

Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Abdominal pain
Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
Acute left ventricular failure (heart attack)
Acute respiratory failure
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Alopecia (absence of hair from areas of the body)

male:

Anxiety
Asthenia (weakness)
Nikolsky's sign
Rash
Renal failure (kidney dysfunction)
Respiratory disorder (respiratory disease)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Conjunctival hyperaemia (congestion of conjunctival vessels)

What are the common drug interactions of Avelox and Linzess, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chronic kidney disease
Renal failure (kidney dysfunction)
Anxiety
Depression
Gastric cancer (stomach cancer)
Renal injury (kidney injury)

50-59:

Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Maculopathy (a condition or disease of the macula, the small spot in the retina where vision is keenest)
Renal failure (kidney dysfunction)

60+:

Alopecia (absence of hair from areas of the body)
Asthenia (weakness)
Nikolsky's sign
Psychological trauma
Rash
Respiratory disorder (respiratory disease)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Chronic kidney disease

What are the existing conditions these people have? *

Infection: 13 people, 76.47%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 13 people, 76.47%
Pain: 12 people, 70.59%
High Blood Pressure: 11 people, 64.71%
Irritable Bowel Syndrome: 9 people, 52.94%
Nausea (feeling of having an urge to vomit): 9 people, 52.94%
Fungal Infection: 9 people, 52.94%
High Blood Cholesterol: 8 people, 47.06%
Neuralgia (pain in one or more nerves): 8 people, 47.06%
Cough: 8 people, 47.06%

* Approximation only. Some reports may have incomplete information.

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