Captopril and Ketoconazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Captopril (captopril) and Ketoconazole (ketoconazole). Common drug interactions include multiple fractures among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Captopril and Ketoconazole. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Captopril?

Captopril has active ingredients of captopril. It is often used in high blood pressure. eHealthMe is studying from 17,438 Captopril users. Check the latest studies of Captopril.

What is Ketoconazole?

Ketoconazole has active ingredients of ketoconazole. It is often used in fungal infection. eHealthMe is studying from 16,014 Ketoconazole users. Check the latest studies of Ketoconazole.

On Jul, 18, 2026

33 people who take Captopril and Ketoconazole together, and have interactions are studied.

Captopril and Ketoconazole drug interactions.

What are the common drug interactions of Captopril and Ketoconazole, by gender? *:

female:

Multiple fractures
Osteoporosis (bones weak and more likely to break)
Pain
Abdominal distension
Aspartate aminotransferase increased
Asphyxia (a condition in which there is an extreme decrease in the concentration of oxygen in the body)
Atelectasis (partial or complete collapse of the lung)
Blood pressure decreased
Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
Cerebral thrombosis (blood clot in brain)

male:

Pyrexia (fever)
Hypertensive crisis
Platelet count decreased
Abdominal adhesions (inflammation of abdomen)
Anaemia (lack of blood)
Blood cholesterol increased
Blood potassium decreased
Blood triglycerides increased
Body height decreased
Bradycardia (abnormally slow heart action)

What are the common drug interactions of Captopril and Ketoconazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Maternal exposure during pregnancy (use of substance during pregnancy)
Premature labour
Dyslipidaemia (abnormal amount of lipids)

40-49:

Chronic kidney disease
Osteonecrosis (death of bone)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Blood creatinine increased
Bone density decreased
Emotional distress
Hip arthroplasty
Pain
Renal impairment (severely reduced kidney function)

50-59:

Bedridden
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Cystitis (inflammation of the wall of the bladder)
Gastric haemorrhage (bleeding stomach)
Intestinal haemorrhage (bleeding from intestine)

60+:

Pyrexia (fever)
Hypertensive crisis
Blood cholesterol increased
Blood potassium decreased
Blood triglycerides increased
Body height decreased
Bradycardia (abnormally slow heart action)
Carcinoid tumour of the gastrointestinal tract
Cystitis (inflammation of the wall of the bladder)
Dehydration (dryness resulting from the removal of water)

What are the existing conditions these people have? *

Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 8 people, 24.24%
High Blood Cholesterol: 4 people, 12.12%
Acromegaly (body produces too much growth hormone, leading to excess growth of body tissues): 3 people, 9.09%
Prostate Cancer: 3 people, 9.09%
Osteopenia (a condition where bone mineral density is lower than normal): 3 people, 9.09%
Hiv Infection: 3 people, 9.09%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 6.06%
Blood Growth Hormone Abnormal: 2 people, 6.06%
Blood Pressure Abnormal: 2 people, 6.06%
Blood Testosterone Abnormal: 2 people, 6.06%

* Approximation only. Some reports may have incomplete information.

Do you take Captopril and Ketoconazole?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously