Climara and Dermatitis - atopic - a phase IV clinical study of FDA data

Summary:

Dermatitis - atopic is reported as a side effect among people who take Climara (estradiol), especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years also take Fosamax, and have Osteoporosis.

The phase IV clinical study analyzes which people have Dermatitis - atopic when taking Climara. It is created by eHealthMe based on reports of 6,607 people who have side effects when taking Climara from the FDA, and is updated regularly.

What is Climara?

Climara has active ingredients of estradiol. It is often used in hormone replacement therapy. eHealthMe is studying from 6,706 Climara users. Check the latest studies of Climara.

What is Dermatitis - atopic?

Dermatitis - atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder) is found to be associated with 2,008 drugs and 1,973 conditions by eHealthMe. Check the latest studies of Dermatitis - atopic.



On Jul, 18, 2026

6,607 people reported to have side effects when taking Climara.
Among them, 17 people (0.26%) have Dermatitis - atopic.

Could Climara cause Dermatitis - atopic?

Among these 17 people:

How long have people been on Climara when they have Dermatitis - atopic? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 100 %
  • 10+ years: 0.0 %

What is the gender of people who have Dermatitis - atopic when taking Climara? *

  • female: 100 %
  • male: 0.0 %

What is the age of people who have Dermatitis - atopic when taking Climara? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 10 %
  • 50-59: 30 %
  • 60+: 60 %

What are other drugs people take besides Climara? *

  1. Fosamax: 7 people, 41.18%
  2. Prednisone: 5 people, 29.41%
  3. Vagifem: 5 people, 29.41%
  4. Premarin: 3 people, 17.65%
  5. Macrobid: 3 people, 17.65%
  6. Flonase: 3 people, 17.65%
  7. Estring: 3 people, 17.65%
  8. Estrace: 3 people, 17.65%
  9. Esomeprazole Magnesium: 3 people, 17.65%
  10. Paxil: 3 people, 17.65%

What are other side effects people have besides Dermatitis - atopic? *

  1. Osteopenia (a condition where bone mineral density is lower than normal): 10 people, 58.82%
  2. Anaemia Postoperative: 7 people, 41.18%
  3. Aseptic Necrosis (the death of bone tissue due to a lack of blood supply): 7 people, 41.18%
  4. Back Pain: 7 people, 41.18%
  5. Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 7 people, 41.18%
  6. Fungal Infection: 7 people, 41.18%
  7. Temporomandibular Joint Syndrome (pain at the temporomandibular joint due to various causes of increased muscle tension and spasm. it is believed that syndrome is a physical manifestation of psychological stress): 7 people, 41.18%
  8. Obliterative Bronchiolitis (bronchiolar inflammation): 7 people, 41.18%
  9. Interstitial Lung Disease: 7 people, 41.18%
  10. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 35.29%

What are the existing conditions these people have? *

  1. Osteoporosis (bones weak and more likely to break): 5 people, 29.41%
  2. Urinary Tract Infection: 3 people, 17.65%
  3. Skin Disorder (skin disease): 3 people, 17.65%
  4. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 3 people, 17.65%
  5. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 11.76%
  6. Stress And Anxiety: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Climara and have Dermatitis - atopic?

- Check whether Dermatitis - atopic is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Climara:

Dermatitis - atopic treatments and more:

How severe was Dermatitis - atopic and when was it recovered:

Expand to all the drugs that have ingredients of estradiol:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Climara:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Dermatitis - atopic:

Browse all the conditions that are associated with Dermatitis - atopic:


How the study uses the data?

The study uses data from the FDA. It is based on estradiol (the active ingredients of Climara) and Climara (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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