Avinza and Allegra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Avinza (morphine sulfate) and Allegra (fexofenadine hydrochloride). Common drug interactions include fatigue among females and memory impairment among males.

The phase IV clinical study analyzes what interactions people have when they take Avinza and Allegra. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Avinza?

Avinza has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 1,728 Avinza users. Check the latest studies of Avinza.

What is Allegra?

Allegra has active ingredients of fexofenadine hydrochloride. It is often used in allergies. eHealthMe is studying from 75,497 Allegra users. Check the latest studies of Allegra.



On Jul, 20, 2026

38 people who take Avinza and Allegra together, and have interactions are studied.

Avinza and Allegra drug interactions.

What are the common drug interactions of Avinza and Allegra, by gender? *:

female:

  1. Fatigue (feeling of tiredness)
  2. Foot fracture
  3. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  4. Hallucination (an experience involving the perception of something not present)
  5. Heart rate increased
  6. Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
  7. Hyperlipidaemia (presence of excess lipids in the blood)
  8. Hypersensitivity
  9. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
  10. Ill-defined disorder

male:

  1. Memory impairment
  2. Nausea (feeling of having an urge to vomit)
  3. Arachnoiditis (neuropathic disease caused by inflammation of the arachnoid)
  4. Arthralgia (joint pain)
  5. Blood glucose increased
  6. Blood pressure decreased
  7. Blood pressure increased
  8. Candidiasis (candidiasis or thrush is a fungal infection)
  9. Chest pain
  10. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)

What are the common drug interactions of Avinza and Allegra, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Ankylosing spondylitis (type of arthritis affecting the spine)
  2. Somnolence (a state of near-sleep, a strong desire for sleep)

30-39:

  1. Arthralgia (joint pain)
  2. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  3. Diarrhoea
  4. Nausea (feeling of having an urge to vomit)
  5. Chest pain
  6. Dysuria (painful or difficult urination)
  7. Fatigue (feeling of tiredness)
  8. Hypersensitivity
  9. Pyrexia (fever)
  10. Rash

40-49:

  1. Anion gap increased
  2. Blood glucose increased
  3. Small intestinal obstruction (blockage in small intestine)
  4. Type 2 diabetes mellitus
  5. Chronic kidney disease
  6. Death
  7. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  8. Neutrophil percentage increased
  9. Renal failure (kidney dysfunction)
  10. White blood cell count increased

50-59:

  1. Agitation (state of anxiety or nervous excitement)
  2. Bladder neck suspension
  3. Bradycardia (abnormally slow heart action)
  4. Chronic kidney disease
  5. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  6. Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
  7. Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
  8. Drug ineffective
  9. Fall
  10. Foot fracture

60+:

  1. Anxiety
  2. Chest pain
  3. Tongue haematoma (blood clot formation in tongue)
  4. Coagulopathy (blood's ability to clot is impaired)
  5. Depressed mood
  6. Drug ineffective
  7. Epistaxis (bleed from the nose)
  8. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  9. Influenza
  10. Insomnia (sleeplessness)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 23.68%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 9 people, 23.68%
  3. Depression: 5 people, 13.16%
  4. High Blood Pressure: 3 people, 7.89%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 7.89%
  6. Sinusitis (inflammation of sinus): 2 people, 5.26%
  7. Post Laminectomy Syndrome: 2 people, 5.26%
  8. Oesophageal Candidiasis (fungal infection of oesophagus): 2 people, 5.26%
  9. Insomnia (sleeplessness): 2 people, 5.26%
  10. Hiv Test Positive: 2 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Avinza and Allegra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Avinza:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Allegra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Avinza and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Allegra and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on morphine sulfate and fexofenadine hydrochloride (the active ingredients of Avinza and Allegra, respectively), and Avinza and Allegra (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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