Avonex and Aranesp drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Avonex (interferon beta 1a) and Aranesp (darbepoetin alfa). Common drug interactions include feeling cold among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Avonex and Aranesp. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Avonex?

Avonex has active ingredients of interferon beta 1a. It is often used in multiple sclerosis. eHealthMe is studying from 198,544 Avonex users. Check the latest studies of Avonex.

What is Aranesp?

Aranesp has active ingredients of darbepoetin alfa. It is often used in anemia. eHealthMe is studying from 54,331 Aranesp users. Check the latest studies of Aranesp.



On Aug, 03, 2026

20 people who take Avonex and Aranesp together, and have interactions are studied.

Avonex and Aranesp drug interactions.

What are the common drug interactions of Avonex and Aranesp, by gender? *:

female:

  1. Feeling cold
  2. Renal failure chronic (long lasting kidney dysfunction)
  3. Haematocrit decreased
  4. Hot flush (sudden feelings of heat)
  5. Influenza like illness
  6. Muscle spasms (muscle contraction)
  7. Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
  8. Death
  9. Dizziness
  10. Headache (pain in head)

male:

  1. Asthenia (weakness)
  2. Haemoglobin decreased
  3. Headache (pain in head)
  4. Injection site reaction
  5. Insomnia (sleeplessness)
  6. Muscle injury
  7. Vasculitis (inflammation of a blood vessel or blood vessels)

What are the common drug interactions of Avonex and Aranesp, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Papillary thyroid cancer
  2. Pulmonary embolism (blockage of the main artery of the lung)

30-39:

n/a

40-49:

  1. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  2. Temperature intolerance (inability to go in temperature)
  3. Contusion (a type of hematoma of tissue in which capillaries)
  4. Death
  5. Aplasia pure red cell (type of anaemia affecting the precursors to red blood cells but not to white blood cells)
  6. Depression
  7. Disease progression
  8. Dizziness
  9. Erythema (redness of the skin)
  10. Fall

50-59:

  1. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  2. Cartilage atrophy (cartilage extra growth)
  3. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  4. Dermatitis allergic (inflammation of the skin due allergic reaction)
  5. Dizziness
  6. Headache (pain in head)
  7. Hiv test positive
  8. Muscle spasms (muscle contraction)
  9. Muscle spasticity (tight or stiff muscles and an inability to control those muscles)
  10. Myalgia (muscle pain)

60+:

  1. Memory impairment
  2. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  3. Anxiety
  4. Asthenia (weakness)
  5. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  6. Blood creatine phosphokinase increased
  7. Haemoglobin decreased
  8. Headache (pain in head)
  9. Hyperlipidaemia (presence of excess lipids in the blood)
  10. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)

What are the existing conditions these people have? *

  1. Pancreatic Carcinoma (pancreatic cancer): 2 people, 10.00%
  2. High Blood Pressure: 2 people, 10.00%
  3. Breast Cancer: 2 people, 10.00%
  4. Sleep Disorder: 1 person, 5.00%
  5. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 5.00%
  6. Platelet Count Increased: 1 person, 5.00%
  7. Ovarian Cancer (cancer of ovary): 1 person, 5.00%
  8. Nephrogenic Anaemia (anaemia due to kidney disease): 1 person, 5.00%
  9. Metastases To Bone (cancer spreads to bone): 1 person, 5.00%
  10. Malignant Respiratory Tract Neoplasm (cancer tumour of respiratory tract): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Avonex and Aranesp?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Avonex and Aranesp:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Avonex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Aranesp:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Avonex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Aranesp and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on interferon beta 1a and darbepoetin alfa (the active ingredients of Avonex and Aranesp, respectively), and Avonex and Aranesp (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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