Aygestin and Diflucan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Aygestin (norethindrone acetate) and Diflucan (fluconazole). Common drug interactions include anxiety among females.

The phase IV clinical study analyzes what interactions people have when they take Aygestin and Diflucan. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Aygestin?

Aygestin has active ingredients of norethindrone acetate. It is often used in endometriosis. eHealthMe is studying from 1,107 Aygestin users. Check the latest studies of Aygestin.

What is Diflucan?

Diflucan has active ingredients of fluconazole. It is often used in vaginal yeast infection. eHealthMe is studying from 28,471 Diflucan users. Check the latest studies of Diflucan.

On Jul, 26, 2026

14 people who take Aygestin and Diflucan together, and have interactions are studied.

Aygestin and Diflucan drug interactions.

What are the common drug interactions of Aygestin and Diflucan, by gender? *:

female:

Anxiety
Cellulitis (infection under the skin)
Pain
Pruritus (severe itching of the skin)
Pain in extremity
Asthenia (weakness)
Diabetic foot
Erythema (redness of the skin)
Fungal infection
Nausea (feeling of having an urge to vomit)

male:

n/a

What are the common drug interactions of Aygestin and Diflucan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Drug ineffective
Infectious mononucleosis (infection usually caused by the epstein-barr virus)
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Splenomegaly (enlargement of spleen)
Therapeutic response unexpected

40-49:

Obstruction
Rectal haemorrhage (bleeding from anus)
Rhinorrhoea (watery mucus discharge from the nose)
Stress incontinence (leak urine with things like coughing, sneezing or exercise)
Transaminases increased
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Anxiety
Cellulitis (infection under the skin)
Depression
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)

50-59:

Chest pain
Compression fracture (fracture due to pressure caused by injury)
Decreased activity
Dilatation ventricular
Dizziness
Dysphemia (stammering or stuttering)
Dyspnoea (difficult or laboured respiration)
Hemiparesis (weakness on one side of the body)
Hepatic lesion
Hypertension (high blood pressure)

60+:

Injection site haematoma (localized swelling filled with blood at injection site)
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Road traffic accident

What are the existing conditions these people have? *

Pain: 4 people, 28.57%
Menopausal Symptoms: 2 people, 14.29%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 14.29%
Wheezing (a high-pitched whistling sound made while you breath): 1 person, 7.14%
Constipation: 1 person, 7.14%
Depression: 1 person, 7.14%
Disease Recurrence: 1 person, 7.14%
Dysmenorrhea (painful menstruation): 1 person, 7.14%
Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 1 person, 7.14%
Hallucination, Visual (seeing things that aren't there): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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