Azacitidine and Imbruvica drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Azacitidine (azacitidine) and Imbruvica (ibrutinib). Common drug interactions include acute myeloid leukaemia among females and acute myeloid leukaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Azacitidine and Imbruvica. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Azacitidine?

Azacitidine has active ingredients of azacitidine. eHealthMe is studying from 17,184 Azacitidine users. Check the latest studies of Azacitidine.

What is Imbruvica?

Imbruvica has active ingredients of ibrutinib. It is often used in chronic lymphocytic leukemia (cll). eHealthMe is studying from 70,020 Imbruvica users. Check the latest studies of Imbruvica.



On Jul, 28, 2026

11 people who take Azacitidine and Imbruvica together, and have interactions are studied.

Azacitidine and Imbruvica drug interactions.

What are the common drug interactions of Azacitidine and Imbruvica, by gender? *:

female:

  1. Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
  2. Bacteraemia (presence of bacteria in the blood)
  3. Fungal sepsis (whole body infection by fungus)
  4. Fusobacterium infection (bacterial infection)
  5. Immunodeficiency
  6. Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
  7. Mucormycosis (a rare infection caused by organisms that belong to a group of fungi called mucoromycotina)
  8. Mucosal inflammation (infection of mucous membrane)
  9. Oesophageal dilatation (enlarged oesophagus)
  10. Oesophagitis (inflammation of oesophagus)

male:

  1. Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
  2. Neutropenia (an abnormally low number of neutrophils)
  3. Fatigue (feeling of tiredness)
  4. Febrile neutropenia (fever with reduced white blood cells)
  5. Haemoglobin decreased
  6. Hypersomnia (excessive daytime sleepiness (eds))
  7. Injection site pain
  8. Lip swelling
  9. Oesophagitis (inflammation of oesophagus)
  10. Pneumonia fungal

What are the common drug interactions of Azacitidine and Imbruvica, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
  2. Neutropenia (an abnormally low number of neutrophils)
  3. Mucormycosis (a rare infection caused by organisms that belong to a group of fungi called mucoromycotina)
  4. Mucosal inflammation (infection of mucous membrane)
  5. Oesophageal dilatation (enlarged oesophagus)
  6. Oesophagitis (inflammation of oesophagus)
  7. Procedural haemorrhage (procedural bleeding)
  8. Procedural hypotension
  9. Pulmonary embolism (blockage of the main artery of the lung)
  10. Septic embolus (a type of embolism that is infected with bacteria)

What are the existing conditions these people have? *

  1. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 7 people, 63.64%
  2. Diffuse Large B-Cell Lymphoma Stage Iv (cancer of b cells, a type of white blood cell-stage iv): 7 people, 63.64%
  3. Diffuse Large B-Cell Lymphoma Recurrent (recurrent cancer of b cells, a type of white blood cell): 6 people, 54.55%
  4. Acute Myelomonocytic Leukaemia (cancer of the blood-forming organs): 5 people, 45.45%
  5. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 4 people, 36.36%
  6. Waldenstrom's Macroglobulinaemia (cancer affects small lymphocytes (white blood cells)): 1 person, 9.09%
  7. Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Azacitidine and Imbruvica?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Azacitidine and Imbruvica:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Azacitidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Imbruvica:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Azacitidine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Imbruvica and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on azacitidine and ibrutinib (the active ingredients of Azacitidine and Imbruvica, respectively), and Azacitidine and Imbruvica (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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