Azasite and Metformin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Azasite (azithromycin) and Metformin (metformin hydrochloride). Common drug interactions include glaucoma among females and eye disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Azasite and Metformin. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Azasite?

Azasite has active ingredients of azithromycin. It is often used in blepharitis. eHealthMe is studying from 1,370 Azasite users. Check the latest studies of Azasite.

What is Metformin?

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 465,354 Metformin users. Check the latest studies of Metformin.



On Jul, 12, 2026

14 people who take Azasite and Metformin together, and have interactions are studied.

Azasite and Metformin drug interactions.

What are the common drug interactions of Azasite and Metformin, by gender? *:

female:

  1. Glaucoma (increased fluid pressure in the eye with vision loss)
  2. Macular oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken)
  3. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
  4. Nausea (feeling of having an urge to vomit)
  5. Optic disc haemorrhage (bleeding from optic disc)
  6. Pruritus (severe itching of the skin)
  7. Retinopathy hypertensive (acute damage to the retina of the eye due to high blood pressure)
  8. Surgery
  9. Urinary tract infection
  10. Urine ketone body present

male:

  1. Eye disorder
  2. Death
  3. Drug ineffective
  4. Eye irritation
  5. Eye pain
  6. Liver disorder (liver diseases)
  7. Vision blurred

What are the common drug interactions of Azasite and Metformin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Eye irritation
  2. Pemphigus (any of several acute or chronic skin diseases characterized by groups of itching blisters)

50-59:

  1. Chronic kidney disease
  2. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
  3. Urinary tract infection
  4. Urine ketone body present

60+:

  1. Death
  2. Drug ineffective
  3. Surgery
  4. Viral infection
  5. Vision blurred
  6. Eye disorder
  7. Eye irritation
  8. Eye pain
  9. Glaucoma (increased fluid pressure in the eye with vision loss)
  10. Liver disorder (liver diseases)

What are the existing conditions these people have? *

  1. Weight Decreased: 3 people, 21.43%
  2. Migraine (headache): 3 people, 21.43%
  3. Constipation: 3 people, 21.43%
  4. Depression: 3 people, 21.43%
  5. Diarrhea: 3 people, 21.43%
  6. Dry Mouth: 3 people, 21.43%
  7. Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 21.43%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 21.43%
  9. High Blood Cholesterol: 3 people, 21.43%
  10. High Blood Pressure: 3 people, 21.43%

* Approximation only. Some reports may have incomplete information.

Do you take Azasite and Metformin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Azasite and Metformin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Azasite:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Metformin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Azasite and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Metformin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on azithromycin and metformin hydrochloride (the active ingredients of Azasite and Metformin, respectively), and Azasite and Metformin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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