Azasite and Protonix drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Azasite (azithromycin) and Protonix (pantoprazole sodium). Common drug interactions include pain among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Azasite and Protonix. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Azasite?

Azasite has active ingredients of azithromycin. It is often used in blepharitis. eHealthMe is studying from 1,370 Azasite users. Check the latest studies of Azasite.

What is Protonix?

Protonix has active ingredients of pantoprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 132,659 Protonix users. Check the latest studies of Protonix.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 22, 2026

21 people who take Azasite and Protonix together, and have interactions are studied.

What are the common drug interactions of Azasite and Protonix, by gender? *:

female:

Pain
Eye infection
Blood pressure increased
Headache (pain in head)
Limb injury
Urinary tract infection bacterial
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Ear infection
Fall
Foot fracture

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Nephrogenic anaemia (anaemia due to kidney disease)
Adverse event
Anaemia (lack of blood)
Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
Skin cancer

What are the common drug interactions of Azasite and Protonix, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abdominal pain
Abdominal pain upper
Ankle fracture
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Bone pain
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Depression
Disturbance in attention

50-59:

Ectropion (lower eyelid turns outwards)
Erythema (redness of the skin)
Eye swelling
Hypersensitivity
Vision blurred
Chronic kidney disease
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Conjunctival hyperaemia (congestion of conjunctival vessels)
Scleral disorder (disease of sclera)

60+:

Chronic gastritis (long lasting infection of stomach lining)
Nerve injury
Blindness
Cardiac murmur (an heart sound in valve abnormality)
Cough
Crest syndrome (thick, dry and fibrous skin)
Eye infection
Eye inflammation
Heart valve incompetence (heart's valves do not work correctly)
Injection site pain

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 6 people, 28.57%
Pain: 5 people, 23.81%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 19.05%
High Blood Pressure: 3 people, 14.29%
Visual Impairment: 2 people, 9.52%
Uveitis (inflammation of the uvea): 2 people, 9.52%
Migraine (headache): 2 people, 9.52%
Insomnia (sleeplessness): 2 people, 9.52%
High Blood Cholesterol: 2 people, 9.52%
Glaucoma (increased fluid pressure in the eye with vision loss): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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