Azasite and Synthroid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Azasite (azithromycin) and Synthroid (levothyroxine sodium). Common drug interactions include asthenia among females and dysphonia among males.

The phase IV clinical study analyzes what interactions people have when they take Azasite and Synthroid. It is created by eHealthMe based on reports of 59 people who take the same drugs from the FDA, and is updated regularly.

What is Azasite?

Azasite has active ingredients of azithromycin. It is often used in blepharitis. eHealthMe is studying from 1,370 Azasite users. Check the latest studies of Azasite.

What is Synthroid?

Synthroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 249,198 Synthroid users. Check the latest studies of Synthroid.



On Jul, 08, 2026

59 people who take Azasite and Synthroid together, and have interactions are studied.

Azasite and Synthroid drug interactions.

What are the common drug interactions of Azasite and Synthroid, by gender? *:

female:

  1. Asthenia (weakness)
  2. Disability
  3. Essential tremor
  4. Extrasystoles
  5. Memory impairment
  6. Muscle fatigue (a condition in which muscles cannot exert their normal force)
  7. Myalgia (muscle pain)
  8. Sinusitis (inflammation of sinus)
  9. Tenosynovitis (inflammation of the fluid-filled sheath (called the synovium) that surrounds a tendon)
  10. Visual impairment

male:

  1. Dysphonia (speech disorder attributable to a disorder of phonation)
  2. Chronic kidney disease
  3. Dyspepsia (indigestion)
  4. Nephrogenic anaemia (anaemia due to kidney disease)
  5. Parkinson's disease
  6. Renal failure (kidney dysfunction)
  7. Renal injury (kidney injury)

What are the common drug interactions of Azasite and Synthroid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Abdominal pain
  2. Arthralgia (joint pain)
  3. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)

50-59:

  1. Chronic kidney disease

60+:

  1. Nausea (feeling of having an urge to vomit)
  2. Eye irritation
  3. Asthenia (weakness)
  4. Disability
  5. Extrasystoles
  6. Hypotension (abnormally low blood pressure)
  7. Muscle fatigue (a condition in which muscles cannot exert their normal force)
  8. Myalgia (muscle pain)
  9. Pneumonia
  10. Therapeutic response unexpected

What are the existing conditions these people have? *

  1. Sleep Disorder: 22 people, 37.29%
  2. Dry Eyes (lack of adequate tears): 7 people, 11.86%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 10.17%
  4. High Blood Pressure: 5 people, 8.47%
  5. High Blood Cholesterol: 5 people, 8.47%
  6. Cardiac Disorder: 4 people, 6.78%
  7. Migraine (headache): 4 people, 6.78%
  8. Stress And Anxiety: 4 people, 6.78%
  9. Eye Disorder: 4 people, 6.78%
  10. Dry Mouth: 3 people, 5.08%

* Approximation only. Some reports may have incomplete information.

Do you take Azasite and Synthroid?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Azasite and Synthroid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Azasite:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Synthroid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Azasite and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Synthroid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on azithromycin and levothyroxine sodium (the active ingredients of Azasite and Synthroid, respectively), and Azasite and Synthroid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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