Azelastine hydrochloride and Morphine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Azelastine hydrochloride (azelastine hydrochloride) and Morphine (morphine sulfate). Common drug interactions include sinus disorder among females and depression among males.

The phase IV clinical study analyzes what interactions people have when they take Azelastine hydrochloride and Morphine. It is created by eHealthMe based on reports of 58 people who take the same drugs from the FDA, and is updated regularly.

What is Azelastine hydrochloride?

Azelastine hydrochloride has active ingredients of azelastine hydrochloride. It is often used in allergies. eHealthMe is studying from 5,140 Azelastine hydrochloride users. Check the latest studies of Azelastine hydrochloride.

What is Morphine?

Morphine has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 182,913 Morphine users. Check the latest studies of Morphine.

On Jul, 18, 2026

58 people who take Azelastine hydrochloride and Morphine together, and have interactions are studied.

Azelastine hydrochloride and Morphine drug interactions.

What are the common drug interactions of Azelastine Hydrochloride and Morphine, by gender? *:

female:

Sinus disorder (disease of sinus)
Tooth abscess (pus formation in tooth)
Contusion (a type of hematoma of tissue in which capillaries)
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Diarrhoea
Upper respiratory tract infection
Memory impairment
Dermatitis allergic (inflammation of the skin due allergic reaction)
Fungal infection
Malaise (a feeling of general discomfort or uneasiness)

male:

Depression
Diarrhoea
Asthenia (weakness)
Dehydration (dryness resulting from the removal of water)
Fatigue (feeling of tiredness)
Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Abdominal distension
Arthralgia (joint pain)
Catheter site discharge

What are the common drug interactions of Azelastine Hydrochloride and Morphine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
Abdominal pain upper
Administration site pain
Arthralgia (joint pain)
Blood creatinine increased
Contusion (a type of hematoma of tissue in which capillaries)
Device related infection
Fatigue (feeling of tiredness)
Impaired gastric emptying
Nausea (feeling of having an urge to vomit)

30-39:

n/a

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone density decreased
Depression
Emotional distress
Fatigue (feeling of tiredness)
Hip fracture
Multiple fractures
Osteoporosis (bones weak and more likely to break)
Tooth loss

50-59:

Concussion (short loss of normal brain function in response to a head injury)
Cough
Cystitis (inflammation of the wall of the bladder)
Death
Dehydration (dryness resulting from the removal of water)
Depressed mood
Drug hypersensitivity
Dyspnoea (difficult or laboured respiration)
Dysuria (painful or difficult urination)
Escherichia urinary tract infection (urinary tract infection by escherichia coli)

60+:

Cough
Pneumonia
Headache (pain in head)
Skin discomfort (skin pain/irritation)
Staphylococcal infection (an infection with staphylococcus bacteria)
Upper respiratory tract infection
Vertigo
Vomiting
Hypersensitivity
Infusion site extravasation (flow of (blood or lymph) from infusion site)

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 11 people, 18.97%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 8 people, 13.79%
Bacterial Infection: 6 people, 10.34%
Dehydration (dryness resulting from the removal of water): 6 people, 10.34%
Asthma: 5 people, 8.62%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 8.62%
Immune System Disorder: 5 people, 8.62%
Depression: 4 people, 6.90%
Gait Disturbance: 4 people, 6.90%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 6.90%

* Approximation only. Some reports may have incomplete information.

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