Azelastine and Tikosyn drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Azelastine (azelastine hydrochloride) and Tikosyn (dofetilide). Common drug interactions include cough among females and hypotension among males.

The phase IV clinical study analyzes what interactions people have when they take Azelastine and Tikosyn. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Azelastine?

Azelastine has active ingredients of azelastine hydrochloride. It is often used in allergies. eHealthMe is studying from 17,400 Azelastine users. Check the latest studies of Azelastine.

What is Tikosyn?

Tikosyn has active ingredients of dofetilide. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 12,202 Tikosyn users. Check the latest studies of Tikosyn.

On Jul, 21, 2026

17 people who take Azelastine and Tikosyn together, and have interactions are studied.

Azelastine and Tikosyn drug interactions.

What are the common drug interactions of Azelastine and Tikosyn, by gender? *:

female:

Cough
Dysphonia (speech disorder attributable to a disorder of phonation)
Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)
Choking (mechanical obstruction of the flow of air from the environment into the lungs)
Dizziness
Hot flush (sudden feelings of heat)
Productive cough
Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Infusion site haemorrhage (bleeding from infusion site)

male:

Hypotension (abnormally low blood pressure)
Abdominal distension
Blood lactate dehydrogenase increased
Blood potassium decreased
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Diarrhoea
Dizziness
Dyspepsia (indigestion)
Dyspnoea (difficult or laboured respiration)
Extrasystoles

What are the common drug interactions of Azelastine and Tikosyn, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Dyspnoea (difficult or laboured respiration)

50-59:

n/a

60+:

Dizziness
Dysphonia (speech disorder attributable to a disorder of phonation)
Abdominal pain upper
Anaemia (lack of blood)
Asthenia (weakness)
Beta 2 microglobulin increased
Blood creatinine increased
Blood immunoglobulin a decreased
Blood immunoglobulin g decreased
Blood immunoglobulin m decreased

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 5 people, 29.41%
High Blood Pressure: 4 people, 23.53%
Pain: 3 people, 17.65%
Glaucoma (increased fluid pressure in the eye with vision loss): 3 people, 17.65%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 17.65%
Hypersensitivity: 2 people, 11.76%
Depression: 2 people, 11.76%
Diarrhea: 2 people, 11.76%
Nerve Injury: 2 people, 11.76%
Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 11.76%

* Approximation only. Some reports may have incomplete information.

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