Zyrtec and Tarka drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zyrtec (cetirizine hydrochloride) and Tarka (trandolapril; verapamil hydrochloride). Common drug interactions include diarrhoea among females and cellulitis among males.

The phase IV clinical study analyzes what interactions people have when they take Zyrtec and Tarka. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Zyrtec?

Zyrtec has active ingredients of cetirizine hydrochloride. It is often used in allergies. eHealthMe is studying from 114,619 Zyrtec users. Check the latest studies of Zyrtec.

What is Tarka?

Tarka has active ingredients of trandolapril; verapamil hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 2,409 Tarka users. Check the latest studies of Tarka.



On Jul, 21, 2026

22 people who take Zyrtec and Tarka together, and have interactions are studied.

Zyrtec and Tarka drug interactions.

What are the common drug interactions of Zyrtec and Tarka, by gender? *:

female:

  1. Diarrhoea
  2. Hepatitis (inflammation of the liver)
  3. Pancreatitis (inflammation of pancreas)
  4. Renal failure acute (rapid kidney dysfunction)
  5. Blood cholesterol increased
  6. Drug ineffective
  7. Fall
  8. Gingival abscess (pus in gums)
  9. Hand fracture
  10. Pyrexia (fever)

male:

  1. Cellulitis (infection under the skin)
  2. Cyanopsia (defect of vision in which objects appear tinged with blue)
  3. Glossodynia (a burning or painful sensation in the tongue)
  4. Growth hormone deficiency
  5. Heart rate increased
  6. Oral candidiasis (fungal infection of mouth)
  7. Swelling
  8. Swollen tongue (swelling of tongue)
  9. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  10. Throat tightness

What are the common drug interactions of Zyrtec and Tarka, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Diarrhoea
  2. Hepatitis (inflammation of the liver)
  3. Pancreatitis (inflammation of pancreas)
  4. Renal failure acute (rapid kidney dysfunction)
  5. Gingival abscess (pus in gums)
  6. Pyrexia (fever)
  7. Ageusia (loss of taste functions of the tongue)
  8. Gallbladder disorder
  9. Glossodynia (a burning or painful sensation in the tongue)
  10. Hepatitis a antibody positive

60+:

  1. Blood cholesterol increased
  2. Drug ineffective
  3. Heart rate increased
  4. Renal failure chronic (long lasting kidney dysfunction)
  5. Respiratory tract congestion (blockage on respiratory system)
  6. Swelling
  7. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  8. Thermal burn (burn by heat)
  9. Throat tightness
  10. Fall

What are the existing conditions these people have? *

  1. Erection Problems: 3 people, 13.64%
  2. Asthma: 3 people, 13.64%
  3. Type 2 Diabetes: 2 people, 9.09%
  4. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 9.09%
  5. Osteoporosis (bones weak and more likely to break): 2 people, 9.09%
  6. Multiple Allergies (allergy to multiple agents): 2 people, 9.09%
  7. Growth Hormone Deficiency: 2 people, 9.09%
  8. Depression: 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Zyrtec and Tarka?

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- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Zyrtec and Tarka:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zyrtec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Tarka:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zyrtec and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tarka and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on cetirizine hydrochloride and trandolapril; verapamil hydrochloride (the active ingredients of Zyrtec and Tarka, respectively), and Zyrtec and Tarka (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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