Azilect and Ambien drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Azilect (rasagiline mesylate) and Ambien (zolpidem tartrate). Common drug interactions include hyperparathyroidism secondary among females and pathological gambling among males.

The phase IV clinical study analyzes what interactions people have when they take Azilect and Ambien. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.

What is Azilect?

Azilect has active ingredients of rasagiline mesylate. It is often used in parkinson's disease. eHealthMe is studying from 8,622 Azilect users. Check the latest studies of Azilect.

What is Ambien?

Ambien has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 93,519 Ambien users. Check the latest studies of Ambien.

On Jul, 15, 2026

57 people who take Azilect and Ambien together, and have interactions are studied.

What are the common drug interactions of Azilect and Ambien, by gender? *:

female:

Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Hypotension (abnormally low blood pressure)
Increased appetite
Injury
Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
Local swelling (swelling at the site of some application of substance or injury)
Localised infection (infection at the single location)
Memory impairment
Migraine (headache)

male:

Pathological gambling
Hyperphagia (an abnormal appetite for food)
Injury
Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
Psychotic disorder
Suicidal ideation
Anxiety
Fall
Fatigue (feeling of tiredness)
Joint swelling

What are the common drug interactions of Azilect and Ambien, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anxiety
Adverse event
Drug ineffective
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Blood pressure increased
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Emotional distress
Gambling
General physical health deterioration (weak health status)
Headache (pain in head)

50-59:

Weight decreased
Abnormal behaviour
Anxiety
Compulsive shopping
Death
Depression
Heart rate irregular
Hypersexuality
Hypertension (high blood pressure)
Pathological gambling

60+:

Fall
Dyskinesia (abnormality or impairment of voluntary movement)
Thrombocytopenia (decrease of platelets in blood)
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Barrett's oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach)
Blood creatine increased
Blood creatinine increased
Blood urine present
Chills (felling of cold)
Cholecystitis chronic (long lasting infection of gallbladder)

What are the existing conditions these people have? *

Pain: 14 people, 24.56%
Depression: 11 people, 19.30%
Sleep Disorder: 6 people, 10.53%
Hallucinations (sensations that appear real but are created by your mind): 6 people, 10.53%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 5 people, 8.77%
Nasal Discharge (discharge from nose): 5 people, 8.77%
High Blood Cholesterol: 5 people, 8.77%
Genital Herpes (herpes infection of genital): 5 people, 8.77%
Curvature Of The Penis: 5 people, 8.77%
Cognitive Disorder (mental health disorders affects learning, memory, perception, and problem solving): 5 people, 8.77%

* Approximation only. Some reports may have incomplete information.

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