Azilect and Prolia drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Azilect (rasagiline mesylate) and Prolia (denosumab). Common drug interactions include fall among females and choking among males.

The phase IV clinical study analyzes what interactions people have when they take Azilect and Prolia. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.

What is Azilect?

Azilect has active ingredients of rasagiline mesylate. It is often used in parkinson's disease. eHealthMe is studying from 8,622 Azilect users. Check the latest studies of Azilect.

What is Prolia?

Prolia has active ingredients of denosumab. It is often used in osteoporosis. eHealthMe is studying from 151,389 Prolia users. Check the latest studies of Prolia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

46 people who take Azilect and Prolia together, and have interactions are studied.

What are the common drug interactions of Azilect and Prolia, by gender? *:

female:

Fall
Hallucination (an experience involving the perception of something not present)
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Nausea (feeling of having an urge to vomit)
Abdominal injury
Cough
Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Mobility decreased (ability to move is reduced)
Muscle contractions involuntary (uncontrolled muscle contraction)

male:

Choking (mechanical obstruction of the flow of air from the environment into the lungs)
Dysphagia (a condition in which swallowing is difficult or painful)
Arthralgia (joint pain)
Infection
Intraocular pressure increased
Pain in extremity
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Oesophageal food impaction (blockage of oesophagus by food)
Weight decreased
Back pain

What are the common drug interactions of Azilect and Prolia, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Muscle contractions involuntary (uncontrolled muscle contraction)

60+:

Fall
Nausea (feeling of having an urge to vomit)
Mobility decreased (ability to move is reduced)
Oesophageal food impaction (blockage of oesophagus by food)
Weight decreased
Anxiety
Blindness unilateral
Chest pain
Constipation
Cough

What are the existing conditions these people have? *

Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 6 people, 13.04%
Hallucinations (sensations that appear real but are created by your mind): 4 people, 8.70%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 8.70%
Delusion (a false belief or opinion): 4 people, 8.70%
Restless Leg Syndrome (a powerful urge to move your legs): 3 people, 6.52%
Rapid Eye Movements Sleep Abnormal: 3 people, 6.52%
Memory Loss: 3 people, 6.52%
Disturbance In Attention: 3 people, 6.52%
Depression: 3 people, 6.52%
Chronic Thyroiditis (long lasting inflammation of thyroid gland): 3 people, 6.52%

* Approximation only. Some reports may have incomplete information.

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