Azithromycin and Nicotrol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Azithromycin (azithromycin) and Nicotrol (nicotine). Common drug interactions include joint dislocation among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Azithromycin and Nicotrol. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Azithromycin?

Azithromycin has active ingredients of azithromycin. It is often used in sinusitis. eHealthMe is studying from 40,716 Azithromycin users. Check the latest studies of Azithromycin.

What is Nicotrol?

Nicotrol has active ingredients of nicotine. eHealthMe is studying from 4,104 Nicotrol users. Check the latest studies of Nicotrol.



On Jul, 07, 2026

13 people who take Azithromycin and Nicotrol together, and have interactions are studied.

Azithromycin and Nicotrol drug interactions.

What are the common drug interactions of Azithromycin and Nicotrol, by gender? *:

female:

  1. Joint dislocation (a joint position is changed from normal position)
  2. Joint effusion (presence of extra fluid in joint covering)
  3. Joint injury
  4. Liver injury
  5. Malaise (a feeling of general discomfort or uneasiness)
  6. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  7. Micturition urgency (urgency to pass the urine)
  8. Mitral valve incompetence (inefficient heart valve)
  9. Mood altered (changes in mood)
  10. Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)

male:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Renal failure (kidney dysfunction)
  4. Spinal compression fracture (fracture due to spinal compression on bone)
  5. Depression
  6. Impaired work ability
  7. Intervertebral disc degeneration (spinal disc degeneration)
  8. Lethargy (tiredness)
  9. Nausea (feeling of having an urge to vomit)
  10. Osteoporosis (bones weak and more likely to break)

What are the common drug interactions of Azithromycin and Nicotrol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Nausea (feeling of having an urge to vomit)
  2. Thermal burn (burn by heat)

30-39:

n/a

40-49:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Emotional distress
  4. Foot fracture
  5. Osteoporosis (bones weak and more likely to break)
  6. Pain
  7. Tibia fracture (fracture of lower leg bone)

50-59:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  4. Anxiety
  5. Blood creatinine increased
  6. Decreased activity
  7. Emotional distress
  8. Fatigue (feeling of tiredness)
  9. Hypertension (high blood pressure)
  10. Pain

60+:

  1. Drug ineffective
  2. Dyspnoea (difficult or laboured respiration)
  3. Impaired work ability
  4. Intervertebral disc degeneration (spinal disc degeneration)
  5. Lethargy (tiredness)
  6. Nicotine dependence
  7. Osteopenia (a condition where bone mineral density is lower than normal)
  8. Osteoporosis (bones weak and more likely to break)
  9. Pain
  10. Quality of life decreased

What are the existing conditions these people have? *

  1. Hiv Infection: 6 people, 46.15%
  2. Pain: 5 people, 38.46%
  3. Quit Smoking: 4 people, 30.77%
  4. High Blood Cholesterol: 3 people, 23.08%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 23.08%
  6. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 2 people, 15.38%
  7. Nausea (feeling of having an urge to vomit): 2 people, 15.38%
  8. Diabetes: 2 people, 15.38%
  9. Bacterial Infection: 1 person, 7.69%
  10. Cough: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Azithromycin and Nicotrol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Azithromycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Nicotrol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Azithromycin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nicotrol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on azithromycin and nicotine (the active ingredients of Azithromycin and Nicotrol, respectively), and Azithromycin and Nicotrol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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