Azithromycin and Peginterferon drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Azithromycin (azithromycin) and Peginterferon (peginterferon alfa-2a; ribavirin). Common drug interactions include muscle spasms among females and nausea among males.
The phase IV clinical study analyzes what interactions people have when they take Azithromycin and Peginterferon. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.
What is Azithromycin?
Azithromycin has active ingredients of azithromycin. It is often used in sinusitis. eHealthMe is studying from 40,716 Azithromycin users. Check the latest studies of Azithromycin.
What is Peginterferon?
Peginterferon has active ingredients of peginterferon alfa-2a; ribavirin. It is often used in hepatitis c. eHealthMe is studying from 13,778 Peginterferon users. Check the latest studies of Peginterferon.
12 people who take Azithromycin and Peginterferon together, and have interactions are studied.

What are the common drug interactions of Azithromycin and Peginterferon, by gender? *:
female:
- Muscle spasms (muscle contraction)
- Bulimia nervosa (eating disorder characterized by recurrent binge eating, followed by compensatory behaviours)
- Bradycardia (abnormally slow heart action)
- Circulatory collapse
- Hypersensitivity
- Hypotension (abnormally low blood pressure)
- Nausea (feeling of having an urge to vomit)
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Abdominal discomfort
- Alanine aminotransferase increased
male:
- Nausea (feeling of having an urge to vomit)
- Alanine aminotransferase increased
- Influenza like illness
- Nasopharyngitis (inflammation of the nasopharynx)
- Oral herpes (viral infection of mouth)
- Pruritus (severe itching of the skin)
- Restlessness (not able to rest)
- Skin irritation
- Vertigo
- Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
What are the common drug interactions of Azithromycin and Peginterferon, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Nausea (feeling of having an urge to vomit)
- Alanine aminotransferase increased
- Muscle spasms (muscle contraction)
- Drug dependence
- Bulimia nervosa (eating disorder characterized by recurrent binge eating, followed by compensatory behaviours)
- Bradycardia (abnormally slow heart action)
- Circulatory collapse
- Hypersensitivity
- Hypotension (abnormally low blood pressure)
- Syncope (loss of consciousness with an inability to maintain postural tone)
40-49:
- Haemarthrosis (haemarthrosis is where blood is able to enter the joint capsule)
- Psychotic disorder
50-59:
- Anaemia (lack of blood)
- Pneumonitis (inflammation of the walls of the alveoli in the lungs)
- Pyrexia (fever)
- Thrombocytopenia (decrease of platelets in blood)
- Leukopenia (less number of white blood cells in blood)
- Neutropenia (an abnormally low number of neutrophils)
- Oral fungal infection
- Oral pain
60+:
- Abdominal discomfort
- Blood calcium decreased
- Electrocardiogram qt prolonged
- Infusion related reaction
- Skin reaction
- Chest pain
- Dyspepsia (indigestion)
- Eructation (release of gas from the digestive tract)
- Essential thrombocythaemia (chronic blood cancer)
- Nausea (feeling of having an urge to vomit)
What are the existing conditions these people have? *
- Hiv Infection: 3 people, 25.00%
- Hairy Cell Leukaemia (a type of blood cancer): 2 people, 16.67%
- Swallowing Pain Or Burning: 1 person, 8.33%
- Otitis Externa (external ear infection): 1 person, 8.33%
- Osteoporosis (bones weak and more likely to break): 1 person, 8.33%
- Joint Pain: 1 person, 8.33%
- Haemorrhage (bleeding): 1 person, 8.33%
- Fungal Infection: 1 person, 8.33%
- Drug Dependence: 1 person, 8.33%
- Chondrocalcinosis (crystal deposition disease): 1 person, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Azithromycin and Peginterferon?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Azithromycin (40,716 reports)
- Peginterferon (13,778 reports)
Browse all drug interactions of Azithromycin and Peginterferon:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Azithromycin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Peginterferon:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Azithromycin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Peginterferon and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on azithromycin and peginterferon alfa-2a; ribavirin (the active ingredients of Azithromycin and Peginterferon, respectively), and Azithromycin and Peginterferon (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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