Rifater and Lipase increased - a phase IV clinical study of FDA data

Summary:

Lipase increased is reported as a side effect among people who take Rifater (isoniazid; pyrazinamide; rifampin), especially for people who are male, 20-29 old, have been taking the drug for 1 - 6 months also take Myambutol, and have Lymph node tuberculosis.

The phase IV clinical study analyzes which people have Lipase increased when taking Rifater. It is created by eHealthMe based on reports of 1,061 people who have side effects when taking Rifater from the FDA, and is updated regularly.

What is Rifater?

Rifater has active ingredients of isoniazid; pyrazinamide; rifampin. eHealthMe is studying from 1,069 Rifater users. Check the latest studies of Rifater.

What is Lipase increased?

Lipase increased is found to be associated with 846 drugs and 1,029 conditions by eHealthMe. Check the latest studies of Lipase increased.



On Aug, 04, 2026

1,061 people reported to have side effects when taking Rifater.
Among them, 12 people (1.13%) have Lipase increased.

Could Rifater cause Lipase increased?

Among these 12 people:

How long have people been on Rifater when they have Lipase increased? *

  • < 1 month: 27.27 %
  • 1 - 6 months: 72.73 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Lipase increased when taking Rifater? *

  • female: 33.33 %
  • male: 66.67 %

What is the age of people who have Lipase increased when taking Rifater? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 50.0 %
  • 30-39: 8.33 %
  • 40-49: 16.67 %
  • 50-59: 0.0 %
  • 60+: 25.0 %

What are other drugs people take besides Rifater? *

  1. Myambutol: 6 people, 50.00%
  2. Rocephin: 2 people, 16.67%
  3. Allopurinol: 2 people, 16.67%
  4. Effexor: 2 people, 16.67%
  5. Flagyl: 2 people, 16.67%
  6. Zovirax: 1 person, 8.33%
  7. Fluconazole: 1 person, 8.33%
  8. Actonel: 1 person, 8.33%
  9. Arava: 1 person, 8.33%
  10. Bactrim: 1 person, 8.33%

What are other side effects people have besides Lipase increased? *

  1. Blood Bilirubin Increased: 7 people, 58.33%
  2. Cytolytic Hepatitis (dissolution or destruction of a liver cell): 5 people, 41.67%
  3. Aspartate Aminotransferase Increased: 5 people, 41.67%
  4. Eosinophilia (eosinophil count in the peripheral blood exceeds): 5 people, 41.67%
  5. Alanine Aminotransferase Increased: 5 people, 41.67%
  6. Blood Alkaline Phosphatase Increased: 5 people, 41.67%
  7. Hepatic Failure (liver failure): 4 people, 33.33%
  8. Hepatitis (inflammation of the liver): 4 people, 33.33%
  9. Abdominal Pain: 3 people, 25.00%
  10. Nausea And Vomiting: 3 people, 25.00%

What are the existing conditions these people have? *

  1. Lymph Node Tuberculosis: 5 people, 41.67%
  2. Peritoneal Tuberculosis: 2 people, 16.67%
  3. Gout (uric acid crystals building up in the body): 2 people, 16.67%
  4. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 8.33%
  5. Pulmonary Tuberculosis (lungs tuberculosis): 1 person, 8.33%
  6. Pain In Extremity: 1 person, 8.33%
  7. Oral Candidiasis (fungal infection of mouth): 1 person, 8.33%
  8. Juvenile Arthritis (arthritis-related condition that develops in children or teenagers): 1 person, 8.33%
  9. Hiv Infection: 1 person, 8.33%
  10. Herpetic Gingivostomatitis (inflammation of the mouth caused by herpes simplex virus): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Rifater and have Lipase increased?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Rifater:

Lipase increased treatments and more:

How severe was Lipase increased and when was it recovered:

Expand to all the drugs that have ingredients of isoniazid; pyrazinamide; rifampin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Rifater:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Lipase increased:

Browse all the conditions that are associated with Lipase increased:


How the study uses the data?

The study uses data from the FDA. It is based on isoniazid; pyrazinamide; rifampin (the active ingredients of Rifater) and Rifater (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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