Azor and Metformin hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Azor (amlodipine besylate; olmesartan medoxomil) and Metformin hydrochloride (metformin hydrochloride). Common drug interactions include syncope among females and diabetes mellitus inadequate control among males.

The phase IV clinical study analyzes what interactions people have when they take Azor and Metformin hydrochloride. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Azor?

Azor has active ingredients of amlodipine besylate; olmesartan medoxomil. It is often used in high blood pressure. eHealthMe is studying from 3,922 Azor users. Check the latest studies of Azor.

What is Metformin hydrochloride?

Metformin hydrochloride has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 58,646 Metformin hydrochloride users. Check the latest studies of Metformin hydrochloride.



On Jul, 11, 2026

18 people who take Azor and Metformin hydrochloride together, and have interactions are studied.

Azor and Metformin hydrochloride drug interactions.

What are the common drug interactions of Azor and Metformin Hydrochloride, by gender? *:

female:

  1. Syncope (loss of consciousness with an inability to maintain postural tone)
  2. Tenosynovitis (inflammation of the fluid-filled sheath (called the synovium) that surrounds a tendon)
  3. Ulcerative keratitis (ulcerative inflammation of the cornea)
  4. Urinary retention (the inability to completely or partially empty the bladder)
  5. Uveitis (inflammation of the uvea)
  6. Viral infection
  7. Vision blurred
  8. Visual acuity reduced (reduced clearness of vision)
  9. Visual impairment
  10. Vomiting

male:

  1. Diabetes mellitus inadequate control
  2. Acute left ventricular failure (heart attack)
  3. Chronic kidney disease
  4. Concussion (short loss of normal brain function in response to a head injury)
  5. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  6. Erythema (redness of the skin)
  7. Essential hypertension (primary hypertension)
  8. Eye injury
  9. Eye irritation
  10. Eye pain

What are the common drug interactions of Azor and Metformin Hydrochloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
  2. Concussion (short loss of normal brain function in response to a head injury)
  3. Laceration (tearing of soft body tissue)
  4. Rib fracture
  5. Suicide attempt
  6. Wrist fracture

40-49:

  1. Erythema (redness of the skin)
  2. Feeling hot
  3. Flushing (the warm, red condition of human skin)
  4. High density lipoprotein decreased

50-59:

  1. Diabetes mellitus inadequate control
  2. Acute left ventricular failure (heart attack)
  3. Blood glucose fluctuation
  4. Cardiac disorder
  5. Cardiac failure congestive
  6. Cardiomegaly (increased size of heart than normal)
  7. Cardiomyopathy (weakening of the heart muscle)
  8. Cataract (clouding of the lens inside the eye)
  9. Chronic kidney disease
  10. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)

60+:

  1. Asthenia (weakness)
  2. Cardiac failure congestive
  3. Blood glucose decreased
  4. Blood pressure decreased
  5. Cataract (clouding of the lens inside the eye)
  6. Chest discomfort
  7. Corneal abrasion (loss of the surface of cornea)
  8. Cough
  9. Dizziness
  10. Dry eye (lack of adequate tears)

What are the existing conditions these people have? *

  1. High Blood Cholesterol: 3 people, 16.67%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 16.67%
  3. Multiple Myeloma (cancer of the plasma cells): 2 people, 11.11%
  4. Coronary Heart Disease (narrowing or blockage of the coronary arteries): 2 people, 11.11%
  5. Depression: 2 people, 11.11%
  6. Urination - Excessive Volume: 2 people, 11.11%
  7. Sleep Disorder: 2 people, 11.11%
  8. Stress And Anxiety: 2 people, 11.11%
  9. Pain: 1 person, 5.56%
  10. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Azor and Metformin hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Azor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Metformin hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Azor and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Metformin hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate; olmesartan medoxomil and metformin hydrochloride (the active ingredients of Azor and Metformin hydrochloride, respectively), and Azor and Metformin hydrochloride (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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