Azor and Zoloft drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Azor (amlodipine besylate; olmesartan medoxomil) and Zoloft (sertraline hydrochloride). Common drug interactions include flatulence among females and malaise among males.

The phase IV clinical study analyzes what interactions people have when they take Azor and Zoloft. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Azor?

Azor has active ingredients of amlodipine besylate; olmesartan medoxomil. It is often used in high blood pressure. eHealthMe is studying from 3,922 Azor users. Check the latest studies of Azor.

What is Zoloft?

Zoloft has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 138,798 Zoloft users. Check the latest studies of Zoloft.

On Jul, 31, 2026

37 people who take Azor and Zoloft together, and have interactions are studied.

What are the common drug interactions of Azor and Zoloft, by gender? *:

female:

Flatulence (flatus expelled through the anus)
Foot fracture
Furuncle (infection of the hair follicle)
Gait disturbance
Gastroenteritis norovirus (inflammation of stomach and intestine caused by norovirus infection)
Helicobacter infection (helicobacter pylori (h. pylori) infects stomach)
Hemiparesis (weakness on one side of the body)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Hypopnoea (decrease in the breathing rate)
Insomnia (sleeplessness)

male:

Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)
Fatigue (feeling of tiredness)
Influenza like illness
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Barrett's oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach)
Breast cancer
Dizziness
Gastric cancer (stomach cancer)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

What are the common drug interactions of Azor and Zoloft, by age (0-1 to 60+)? *:

0-1:

Cough
Drug ineffective
Dry throat
Dysphonia (speech disorder attributable to a disorder of phonation)
Lethargy (tiredness)
Sedation
Sleep disorder
Suicidal ideation

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Loss of employment
Migraine (headache)
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
Non-cardiac chest pain
Pain
Weight increased
Fall
Sudden death
Back pain
Decreased activity

50-59:

Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Irritable bowel syndrome
Lactose intolerance (inability to digest lactose)
Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract)
Polyp
Rectocele (a bulging of the front wall of the rectum into the back wall of the vagina)
Hypersensitivity
Rash

60+:

Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)
Drug intolerance (drug sensitivity)
Influenza like illness
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Anal fissure
Barrett's oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach)
Breast cancer
Chills (felling of cold)
Dizziness

What are the existing conditions these people have? *

Pain: 6 people, 16.22%
High Blood Cholesterol: 6 people, 16.22%
Insomnia (sleeplessness): 5 people, 13.51%
Stress And Anxiety: 4 people, 10.81%
Constipation: 4 people, 10.81%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 10.81%
Urinary Incontinence (inability to control the flow of urine and involuntary urination): 3 people, 8.11%
Indigestion: 3 people, 8.11%
Prostate Cancer: 3 people, 8.11%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 3 people, 8.11%

* Approximation only. Some reports may have incomplete information.

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