B12 and Cequa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take B12 (cobalamin) and Cequa (cyclosporine). Common drug interactions include arthralgia among females and gastric disorder among males.

The phase IV clinical study analyzes what interactions people have when they take B12 and Cequa. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is B12?

B12 has active ingredients of cobalamin. It is often used in vitamin b12 deficiency. eHealthMe is studying from 121,894 B12 users. Check the latest studies of B12.

What is Cequa?

Cequa has active ingredients of cyclosporine. eHealthMe is studying from 1,543 Cequa users. Check the latest studies of Cequa.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 29, 2026

23 people who take B12 and Cequa together, and have interactions are studied.

B12 and Cequa drug interactions.

What are the common drug interactions of B12 and Cequa, by gender? *:

female:

  1. Arthralgia (joint pain)
  2. Eye pain
  3. Dizziness
  4. Dry eye (lack of adequate tears)
  5. Peripheral swelling
  6. Adverse drug reaction
  7. Aneurysm (enlargement of an artery caused by a weakening of the artery wall)
  8. Aphasia (damage to the parts of the brain that control language)
  9. Asthenia (weakness)
  10. Blood pressure increased

male:

  1. Gastric disorder (disease of stomach)
  2. Anxiety
  3. Chest pain
  4. Death
  5. Decreased appetite
  6. Dry mouth
  7. Dyspnoea (difficult or laboured respiration)
  8. Mania (a state of abnormally elevated or irritable mood)
  9. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  10. Oral discomfort (pain or irritation in mouth)

What are the common drug interactions of B12 and Cequa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Eye pain
  2. Hospitalisation

50-59:

n/a

60+:

  1. Arthralgia (joint pain)
  2. Fall
  3. Contusion (a type of hematoma of tissue in which capillaries)
  4. Cystitis (inflammation of the wall of the bladder)
  5. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  6. Diarrhoea
  7. Dizziness
  8. Dry eye (lack of adequate tears)
  9. Fungal skin infection
  10. Haemorrhage (bleeding)

What are the existing conditions these people have? *

  1. Neurotrophic Keratopathy (decreased corneal sensitivity and poor corneal healing): 7 people, 30.43%
  2. Dry Eyes (lack of adequate tears): 3 people, 13.04%
  3. Ulcerative Keratitis (ulcerative inflammation of the cornea): 2 people, 8.70%
  4. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 8.70%
  5. Peripheral Swelling: 2 people, 8.70%
  6. Irritable Bowel Syndrome: 2 people, 8.70%
  7. Hypoaesthesia Eye (reduced sense of touch or sensation on eyes): 2 people, 8.70%
  8. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 8.70%
  9. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 8.70%
  10. Autoimmune Disorder (a condition in which the immune system attacks the body's normal substances and tissue): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

Do you take B12 and Cequa?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of B12 and Cequa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of B12:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cequa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between B12 and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cequa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on cobalamin and cyclosporine (the active ingredients of B12 and Cequa, respectively), and B12 and Cequa (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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