B12 and Tylenol w/ codeine no. 3 drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take B12 (cobalamin) and Tylenol w/ codeine no. 3 (acetaminophen; codeine phosphate). Common drug interactions include abnormal behaviour among females and acute myocardial infarction among males.

The phase IV clinical study analyzes what interactions people have when they take B12 and Tylenol w/ codeine no. 3. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is B12?

B12 has active ingredients of cobalamin. It is often used in vitamin b12 deficiency. eHealthMe is studying from 121,894 B12 users. Check the latest studies of B12.

What is Tylenol w/ codeine no. 3?

Tylenol w/ codeine no. 3 has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 4,920 Tylenol w/ codeine no. 3 users. Check the latest studies of Tylenol w/ codeine no. 3.

On Jul, 25, 2026

12 people who take B12 and Tylenol w/ codeine no. 3 together, and have interactions are studied.

B12 and Tylenol w/ codeine no. 3 drug interactions.

What are the common drug interactions of B12 and Tylenol W/ Codeine No. 3, by gender? *:

female:

Abnormal behaviour
Confusion
Memory impairment
Suicidal ideation
Atrioventricular block (heart block)
Cardiac arrest
Dehydration (dryness resulting from the removal of water)
Drug effect decreased
Dysphagia (a condition in which swallowing is difficult or painful)
Erythrocyte sedimentation rate increased

male:

Acute myocardial infarction (acute heart attack)
Asthenia (weakness)
Tinea pedis (a contagious skin infection caused by the ringworm fungus)
Dysarthria (speech disorder)
Dysphagia (a condition in which swallowing is difficult or painful)
Fall
Pleural effusion (water on the lungs)
Spinal compression fracture (fracture due to spinal compression on bone)
Spinal fracture (fracture in one of vertebrae)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)

What are the common drug interactions of B12 and Tylenol W/ Codeine No. 3, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Injection site reaction
Pyrexia (fever)

50-59:

Acute myocardial infarction (acute heart attack)
Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blindness unilateral
Cellulitis (infection under the skin)
Diarrhoea
Headache (pain in head)
Optic ischaemic neuropathy (optic nerve damage due to lack of blood supply)
Skin lesion
Syncope (loss of consciousness with an inability to maintain postural tone)

60+:

Dysphagia (a condition in which swallowing is difficult or painful)
Dysarthria (speech disorder)
Spinal compression fracture (fracture due to spinal compression on bone)
Spinal fracture (fracture in one of vertebrae)
Urinary tract infection
Weight decreased
Fall
Cardiac arrest
Dehydration (dryness resulting from the removal of water)
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)

What are the existing conditions these people have? *

Stress And Anxiety: 3 people, 25.00%
Fatigue (feeling of tiredness): 3 people, 25.00%
Dyspnea (difficult or laboured breathing): 3 people, 25.00%
Diarrhea: 3 people, 25.00%
Diabetes: 3 people, 25.00%
Back Pain: 3 people, 25.00%

* Approximation only. Some reports may have incomplete information.

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