B6 and Zantac drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take B6 (pyridoxine (vitamin b6)) and Zantac (ranitidine hydrochloride). Common drug interactions include chronic kidney disease among females and aortic valve replacement among males.

The phase IV clinical study analyzes what interactions people have when they take B6 and Zantac. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is B6?

B6 has active ingredients of pyridoxine (vitamin b6). eHealthMe is studying from 1,043 B6 users. Check the latest studies of B6.

What is Zantac?

Zantac has active ingredients of ranitidine hydrochloride. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 434,161 Zantac users. Check the latest studies of Zantac.

On Aug, 04, 2026

17 people who take B6 and Zantac together, and have interactions are studied.

What are the common drug interactions of B6 and Zantac, by gender? *:

female:

Chronic kidney disease
Adverse drug reaction
Adverse reaction
Asthenia (weakness)
Burning sensation
Cellulitis (infection under the skin)
Diarrhoea
Dizziness
Erythema (redness of the skin)
Haemoglobin decreased

male:

Aortic valve replacement
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Blood pressure increased
Cataract (clouding of the lens inside the eye)
Death
Heart rate increased
Nail bed disorder (disease of nail bed)
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Psoriasis (immune-mediated disease that affects the skin)
Rash

What are the common drug interactions of B6 and Zantac, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Death

10-19:

n/a

20-29:

Diarrhoea
Haemoglobin decreased
Injection site pain
Mass
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
Nodule (a growth of abnormal tissue)
Rectal haemorrhage (bleeding from anus)

30-39:

n/a

40-49:

Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
Nail bed disorder (disease of nail bed)
Psoriasis (immune-mediated disease that affects the skin)
Rash

50-59:

Chronic kidney disease
Renal failure (kidney dysfunction)

60+:

Aortic valve replacement
Asthenia (weakness)
Burning sensation
Cataract (clouding of the lens inside the eye)
Cellulitis (infection under the skin)
Erythema (redness of the skin)
Hypotension (abnormally low blood pressure)
Lethargy (tiredness)
Loss of consciousness
Lupus-like syndrome (a disease symptom matches with lupus an immune disease)

What are the existing conditions these people have? *

Thyroid Diseases: 6 people, 35.29%
Hyperkalemia (damage to or disease of the kidney): 5 people, 29.41%
High Blood Pressure: 3 people, 17.65%
Urinary Retention (the inability to completely or partially empty the bladder): 2 people, 11.76%
Mania (a state of abnormally elevated or irritable mood): 2 people, 11.76%
Bipolar Disorder (mood disorder): 2 people, 11.76%
Constipation: 2 people, 11.76%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 11.76%
Depression: 2 people, 11.76%
Diabetes: 2 people, 11.76%

* Approximation only. Some reports may have incomplete information.

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