Baclofen and Midol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Baclofen (baclofen) and Midol (ibuprofen). Common drug interactions include hypertension among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Baclofen and Midol. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Baclofen?

Baclofen has active ingredients of baclofen. It is often used in muscle spasms. eHealthMe is studying from 108,664 Baclofen users. Check the latest studies of Baclofen.

What is Midol?

Midol has active ingredients of ibuprofen. It is often used in painful menstrual periods. eHealthMe is studying from 2,635 Midol users. Check the latest studies of Midol.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

18 people who take Baclofen and Midol together, and have interactions are studied.

What are the common drug interactions of Baclofen and Midol, by gender? *:

female:

Hypertension (high blood pressure)
Aphasia (damage to the parts of the brain that control language)
Dehydration (dryness resulting from the removal of water)
Hemiplegia (paralysis of one side of the body)
Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Depression
Dizziness
Fatigue (feeling of tiredness)
Insomnia (sleeplessness)

male:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Aphasia (damage to the parts of the brain that control language)
Blood urine present
Cerebral artery thrombosis (clot formation in brain blood vessels)
Depression
Hemiplegia (paralysis of one side of the body)
Injury
Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)
Pain
Urinary tract infection

What are the common drug interactions of Baclofen and Midol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Hypertension (high blood pressure)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Depression
Dizziness
Fatigue (feeling of tiredness)
Insomnia (sleeplessness)
Migraine (headache)
Nausea (feeling of having an urge to vomit)
Suicidal ideation
Vision blurred

30-39:

Aphasia (damage to the parts of the brain that control language)
Hemiplegia (paralysis of one side of the body)
Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)

40-49:

Abdominal pain upper
Bone pain
Menstrual disorder (disease of menstrual cycle)
Tooth discolouration (a change in colour of teeth)
Tooth injury
Visual impairment

50-59:

n/a

60+:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Aphasia (damage to the parts of the brain that control language)
Blood urine present
Cerebral artery thrombosis (clot formation in brain blood vessels)
Depression
Hemiplegia (paralysis of one side of the body)
Injury
Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)
Pain
Urinary tract infection

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 14 people, 77.78%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 13 people, 72.22%
Birth Control: 5 people, 27.78%
Depression: 5 people, 27.78%
Hypotonia (low muscle tone): 3 people, 16.67%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 16.67%
Urinary Tract Infection: 3 people, 16.67%
Ill-Defined Disorder: 2 people, 11.11%
Constipation: 2 people, 11.11%
Drowsiness: 2 people, 11.11%

* Approximation only. Some reports may have incomplete information.

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