Baclofen and Proamatine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Baclofen (baclofen) and Proamatine (midodrine hydrochloride). Common drug interactions include emotional distress among females and cardiac arrest among males.

The phase IV clinical study analyzes what interactions people have when they take Baclofen and Proamatine. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Baclofen?

Baclofen has active ingredients of baclofen. It is often used in muscle spasms. eHealthMe is studying from 108,662 Baclofen users. Check the latest studies of Baclofen.

What is Proamatine?

Proamatine has active ingredients of midodrine hydrochloride. It is often used in hypotension. eHealthMe is studying from 968 Proamatine users. Check the latest studies of Proamatine.

On Jul, 13, 2026

12 people who take Baclofen and Proamatine together, and have interactions are studied.

Baclofen and Proamatine drug interactions.

What are the common drug interactions of Baclofen and Proamatine, by gender? *:

female:

Emotional distress
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Bone density decreased
Chronic kidney disease
Osteoporosis (bones weak and more likely to break)
Pain
Weight decreased
Abdominal pain
Asthenia (weakness)
Bacterial infection

male:

Cardiac arrest
Abdominal pain
Dizziness
Epistaxis (bleed from the nose)
Fluid overload (too much fluid in the blood)
Gastric polyps (abnormal growth of stomach tissue projecting from a mucous membrane)
Haematemesis (vomiting of blood)
Haemoglobin decreased
Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
Hypersplenism (enlarged spleen and a decrease in one or more types of blood cells)

What are the common drug interactions of Baclofen and Proamatine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Blood pressure systolic increased
Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Headache (pain in head)

40-49:

Abdominal pain
Anaemia (lack of blood)
Ascites (accumulation of fluid in the abdominal cavity)
Aspartate aminotransferase increased
Blood bilirubin increased
Cardiac arrest
Chronic hepatic failure (long lasting liver failure)
Cirrhosis alcoholic (chronic disease of the liver marked by degeneration of cells, inflammation, and fibrous thickening of tissue caused by alcoholism)
Coagulopathy (blood's ability to clot is impaired)
Confusional state

50-59:

Weight decreased
Abdominal pain
Asthenia (weakness)
Bacterial infection
Blood disorder
Diarrhoea
Loss of consciousness
Sleep disorder
Vomiting
Abdominal pain upper

60+:

Cardiac arrest
Asthenia (weakness)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Speech disorder

What are the existing conditions these people have? *

Pain: 4 people, 33.33%
Hypersensitivity: 3 people, 25.00%
Depression: 3 people, 25.00%
Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 3 people, 25.00%
Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 3 people, 25.00%
Nausea (feeling of having an urge to vomit): 3 people, 25.00%
Stress And Anxiety: 3 people, 25.00%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 3 people, 25.00%
Asthma: 2 people, 16.67%
High Blood Cholesterol: 2 people, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Baclofen and Proamatine?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously