Posaconazole and Colace drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Posaconazole (posaconazole) and Colace (docusate ). Common drug interactions include diarrhoea among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Posaconazole and Colace. It is created by eHealthMe based on reports of 59 people who take the same drugs from the FDA, and is updated regularly.

What is Posaconazole?

Posaconazole has active ingredients of posaconazole. eHealthMe is studying from 9,475 Posaconazole users. Check the latest studies of Posaconazole.

What is Colace?

Colace has active ingredients of docusate . It is often used in constipation. eHealthMe is studying from 41,841 Colace users. Check the latest studies of Colace.

On Jul, 13, 2026

59 people who take Posaconazole and Colace together, and have interactions are studied.

Posaconazole and Colace drug interactions.

What are the common drug interactions of Posaconazole and Colace, by gender? *:

female:

Diarrhoea
Disease progression
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Electrocardiogram qt prolonged
Epistaxis (bleed from the nose)
Fall
Fluid overload (too much fluid in the blood)
Gastrointestinal arteriovenous malformation (malformation of arteries and veins in gastrointestinal tract)
Graft versus host disease in intestine (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body and damages intestinal mucosal membrane)
Haemoglobin decreased

male:

Pyrexia (fever)
Thrombocytopenia (decrease of platelets in blood)
Diarrhoea
Fluid overload (too much fluid in the blood)
Heart rate increased
Hepatic steatosis (fatty liver disease)
Muscle strain (an injury to a muscle in which the muscle fibres tear)
Oedema peripheral (superficial swelling)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Abdominal pain

What are the common drug interactions of Posaconazole and Colace, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Encephalopathy (functioning of the brain is affected by some agent or condition)
Fear
Heart rate increased
Hypokalaemia (low potassium)
Leukocytosis (increased white blood cells)
Loss of consciousness
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Muscle rigidity (muscle stiffness)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Neutropenia (an abnormally low number of neutrophils)

20-29:

Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Acute respiratory distress syndrome
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Fluid overload (too much fluid in the blood)
Hypotension (abnormally low blood pressure)
Hypoxia (low oxygen in tissues)
Pneumonia
Pulmonary alveolar haemorrhage (acute bleeding)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

30-39:

Abdominal pain
Arthralgia (joint pain)
Appendicitis (inflammation of the appendix)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Infarction (obstruction of the blood supply to an organ or region of tissue)
Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
Oedema peripheral (superficial swelling)

40-49:

n/a

50-59:

Bone pain
Acute graft versus host disease in skin (acute complication on skin following an allogeneic tissue/blood transplant)
Cough
Death
Dyspnoea (difficult or laboured respiration)
Electrocardiogram qt prolonged
Graft versus host disease in intestine (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body and damages intestinal mucosal membrane)
Hypotension (abnormally low blood pressure)
Mucosal inflammation (infection of mucous membrane)
Multi-organ failure (multisystem organ failure)

60+:

Pyrexia (fever)
Febrile neutropenia (fever with reduced white blood cells)
Muscle strain (an injury to a muscle in which the muscle fibres tear)
Oedema peripheral (superficial swelling)
Asthenia (weakness)
Atelectasis (partial or complete collapse of the lung)
Chest pain
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haemorrhage intracranial (bleeding within the skull)
Haemorrhagic anaemia (anaemia due to excessive bleeding)

What are the existing conditions these people have? *

Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 19 people, 32.20%
Nausea (feeling of having an urge to vomit): 11 people, 18.64%
Pain: 7 people, 11.86%
Nausea And Vomiting: 7 people, 11.86%
Insomnia (sleeplessness): 6 people, 10.17%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 6 people, 10.17%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 6 people, 10.17%
High Blood Pressure: 5 people, 8.47%
Bone Marrow Conditioning Regimen: 5 people, 8.47%
Indigestion: 4 people, 6.78%

* Approximation only. Some reports may have incomplete information.

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