Peridex and Bactrim ds drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Peridex (chlorhexidine gluconate) and Bactrim ds (sulfamethoxazole; trimethoprim). Common drug interactions include anxiety among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Peridex and Bactrim ds. It is created by eHealthMe based on reports of 85 people who take the same drugs from the FDA, and is updated regularly.

What is Peridex?

Peridex has active ingredients of chlorhexidine gluconate. eHealthMe is studying from 2,803 Peridex users. Check the latest studies of Peridex.

What is Bactrim ds?

Bactrim ds has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 17,027 Bactrim ds users. Check the latest studies of Bactrim ds.

On Jul, 13, 2026

85 people who take Peridex and Bactrim ds together, and have interactions are studied.

Peridex and Bactrim ds drug interactions.

What are the common drug interactions of Peridex and Bactrim Ds, by gender? *:

female:

Anxiety
Aortic arteriosclerosis (hardening of the aortic arteries)
Bacterial test positive
Band neutrophil count increased
Blood glucose decreased
Blood glucose increased
Blood urea nitrogen/creatinine ratio increased
Blood urine present
Body temperature fluctuation
Bone density decreased

male:

Dyspnoea (difficult or laboured respiration)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
International normalised ratio increased
Neutropenia (an abnormally low number of neutrophils)
Soft tissue infection
Blood alkaline phosphatase increased
Confusional state
Dyspnoea exertional (breathlessness or shortness of breath)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Inflammation

What are the common drug interactions of Peridex and Bactrim Ds, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abdominal pain
Activated partial thromboplastin time prolonged
Alanine aminotransferase increased
Blood bilirubin increased
International normalised ratio increased
Blood alkaline phosphatase increased
Malaise (a feeling of general discomfort or uneasiness)
Anaphylactic reaction (serious allergic reaction)
Aspartate aminotransferase increased
Fatigue (feeling of tiredness)

20-29:

Alopecia (absence of hair from areas of the body)
Anaemia (lack of blood)
Arthralgia (joint pain)
Brain compression
Breast cancer stage iii
Breast fibrosis (the thickening and scarring of connective tissue, usually as a result of injury in breast)
Breast inflammation
Cerebellar infarction (impaired blood circulation to cerebellum)
Dental caries
Dermoid cyst (an abnormal growth (teratoma) containing epidermis, hair follicles, and sebaceous glands)

30-39:

n/a

40-49:

General physical health deterioration (weak health status)
Hypertension (high blood pressure)
Hypoaesthesia (reduced sense of touch or sensation)
Lacrimation increased
Lymphoedema (localized fluid retention and tissue swelling)
Melanocytic naevus (a type of lesion that contains nevus cells (a type of melanocyte))
Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
Muscle spasms (muscle contraction)
Myositis (inflammation of the muscles)
Onychomycosis (fungal infection of the nail)

50-59:

Dyspnoea (difficult or laboured respiration)
Haemoglobin decreased
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Peripheral swelling
Sepsis (a severe blood infection that can lead to organ failure and death)
Pneumonia
Refractory cancer (cancer that has not responded to treatment)
Lobar pneumonia (a form of pneumonia that affects a large and continuous area of the lobe of a lung)
Pain in jaw

60+:

Dyspnoea (difficult or laboured respiration)
Neutropenia (an abnormally low number of neutrophils)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pleural effusion (water on the lungs)
Renal failure chronic (long lasting kidney dysfunction)
Hypoxia (low oxygen in tissues)
Myeloproliferative disorder (a group of diseases in which the bone marrow makes too many red blood cells, white blood cells, or platelets)
Alveolitis (inflammation in the socket of a tooth)
Arthropathy
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)

What are the existing conditions these people have? *

Stress And Anxiety: 22 people, 25.88%
Multiple Myeloma (cancer of the plasma cells): 19 people, 22.35%
Pain: 13 people, 15.29%
Constipation: 12 people, 14.12%
Breast Cancer Metastatic: 12 people, 14.12%
Nausea (feeling of having an urge to vomit): 11 people, 12.94%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 11 people, 12.94%
Breast Cancer: 11 people, 12.94%
Metastases To Bone (cancer spreads to bone): 9 people, 10.59%
Oral Disorder (mouth disease): 8 people, 9.41%

* Approximation only. Some reports may have incomplete information.

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