Tasmar and Death - a phase IV clinical study of FDA data

Summary:

Death is reported as a side effect among people who take Tasmar (tolcapone), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Neupro, and have Parkinson's disease.

The study is created by eHealthMe based on reports of 1,270 people who have side effects when taking Tasmar from the FDA, and is updated regularly.

What is Tasmar?

Tasmar has active ingredients of tolcapone. eHealthMe is studying from 1,275 Tasmar users. Check the latest studies of Tasmar.

On Jul, 13, 2026

1,270 people reported to have side effects when taking Tasmar.
Among them, 16 people (1.26%) died.

Among these 16 people:

How long have people been on Tasmar when they died? *

What is the gender of people who died when taking Tasmar? *

female: 40 %
male: 60 %

What is the age of people who died when taking Tasmar? *

What are other drugs people take besides Tasmar? *

What are other side effects people have before they died? *

Confusional State: 2 people, 12.50%
Fall: 2 people, 12.50%
Hypotension (abnormally low blood pressure): 2 people, 12.50%
Depressed Level Of Consciousness: 1 person, 6.25%
Fainting (loss of consciousness and postural tone): 1 person, 6.25%
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 1 person, 6.25%
Electrocardiogram Qt Prolonged: 1 person, 6.25%
Dyskinesia Aggravated (abnormality or impairment of voluntary movement): 1 person, 6.25%
Dyskinesia (abnormality or impairment of voluntary movement): 1 person, 6.25%
Dry Mouth: 1 person, 6.25%

What are the existing conditions these people have? *

* Approximation only. Some reports may have incomplete information.

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tasmar:

Tasmar (1,275 reports)

Expand to all the drugs that have ingredients of tolcapone:

Death and drugs with ingredients of tolcapone

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tasmar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Death:

Death (3,129 drugs)

Browse all the conditions that are associated with Death:

Death (3,686 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tolcapone (the active ingredients of Tasmar) and Tasmar (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.