Baclofen and Vigabatrin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Baclofen (baclofen) and Vigabatrin (vigabatrin). Common drug interactions include drug ineffective among females and seizure among males.

The phase IV clinical study analyzes what interactions people have when they take Baclofen and Vigabatrin. It is created by eHealthMe based on reports of 77 people who take the same drugs from the FDA, and is updated regularly.

What is Baclofen?

Baclofen has active ingredients of baclofen. It is often used in muscle spasms. eHealthMe is studying from 108,662 Baclofen users. Check the latest studies of Baclofen.

What is Vigabatrin?

Vigabatrin has active ingredients of vigabatrin. eHealthMe is studying from 4,046 Vigabatrin users. Check the latest studies of Vigabatrin.



On Jul, 08, 2026

77 people who take Baclofen and Vigabatrin together, and have interactions are studied.

Baclofen and Vigabatrin drug interactions.

What are the common drug interactions of Baclofen and Vigabatrin, by gender? *:

female:

  1. Drug ineffective
  2. Adverse event
  3. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  4. Pneumonia
  5. Cardiac arrest
  6. Cardiac failure
  7. Tracheostomy infection (infection of trachea surgical opening)
  8. Depressed level of consciousness
  9. Dystonia (abnormal muscle tone)
  10. Encephalitis (inflammation of the brain)

male:

  1. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  2. Acute respiratory failure
  3. Gastritis (inflammation of stomach)
  4. Pneumonitis (inflammation of the walls of the alveoli in the lungs)
  5. Respiration (transport of oxygen from the outside air to the cells within tissues)
  6. Viral infection
  7. Adverse event
  8. Hypotension (abnormally low blood pressure)
  9. Cardiac arrest
  10. Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)

What are the common drug interactions of Baclofen and Vigabatrin, by age (0-1 to 60+)? *:

0-1:

  1. Drug ineffective
  2. Acute respiratory failure
  3. Bronchiolitis (inflammation of the membranes lining the bronchioles in lungs)
  4. Catarrh (inflammation of mucous membranes, especially of the nose and throat)
  5. Cough
  6. Depressed level of consciousness
  7. Dystonia (abnormal muscle tone)
  8. Encephalitis (inflammation of the brain)
  9. Enterovirus infection
  10. Hypoventilation (too shallow or too slow breathing, which does not meet the needs of the body)

2-9:

  1. Miosis (constriction of the pupil of the eye, resulting from a normal response to an increase in light)
  2. Urinary tract infection
  3. Biliary tract disorder
  4. Gastritis (inflammation of stomach)
  5. Pneumonitis (inflammation of the walls of the alveoli in the lungs)
  6. Respiration (transport of oxygen from the outside air to the cells within tissues)
  7. Viral infection
  8. Hypotension (abnormally low blood pressure)
  9. Somnolence (a state of near-sleep, a strong desire for sleep)
  10. Adverse event

10-19:

  1. Adverse drug reaction
  2. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  3. Hospitalisation
  4. Infection
  5. Pneumonia

20-29:

  1. Bacterial toxaemia (blood contains bacterial toxins)

30-39:

n/a

40-49:

n/a

50-59:

  1. Seizure (abnormal excessive or synchronous neuronal activity in the brain)

60+:

n/a

What are the existing conditions these people have? *

  1. Lennox-Gastaut Syndrome (epilepsy characterized by frequent seizures and different seizure types): 14 people, 18.18%
  2. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 14 people, 18.18%
  3. Infantile Spasms: 11 people, 14.29%
  4. Pneumonia: 8 people, 10.39%
  5. Movement - Uncontrolled Or Slow: 8 people, 10.39%
  6. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 7 people, 9.09%
  7. Pain: 5 people, 6.49%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Baclofen and Vigabatrin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Baclofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Vigabatrin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Baclofen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vigabatrin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on baclofen and vigabatrin (the active ingredients of Baclofen and Vigabatrin, respectively), and Baclofen and Vigabatrin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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