Bactrim ds and Caffeine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bactrim ds (sulfamethoxazole; trimethoprim) and Caffeine (caffeine). Common drug interactions include fall among females and abdominal discomfort among males.

The phase IV clinical study analyzes what interactions people have when they take Bactrim ds and Caffeine. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Bactrim ds?

Bactrim ds has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 17,027 Bactrim ds users. Check the latest studies of Bactrim ds.

What is Caffeine?

Caffeine has active ingredients of caffeine. It is often used in fatigue. eHealthMe is studying from 6,667 Caffeine users. Check the latest studies of Caffeine.

On Jul, 13, 2026

12 people who take Bactrim ds and Caffeine together, and have interactions are studied.

Bactrim ds and Caffeine drug interactions.

What are the common drug interactions of Bactrim Ds and Caffeine, by gender? *:

female:

Fall
Fistula (an abnormal connection or passageway between two)
Gastrointestinal infection (infection of stomach and intestine)
Hyperthermia (body temperature greatly above normal)
Hypotension (abnormally low blood pressure)
Malaise (a feeling of general discomfort or uneasiness)
Nasopharyngitis (inflammation of the nasopharynx)
Placenta praevia (a condition that occurs during pregnancy when the placenta is abnormally placed, and partially or totally covers the cervix)
Premature labour
Premature separation of placenta

male:

Abdominal discomfort
Cellulitis (infection under the skin)
Limb injury
Neuropathy peripheral (surface nerve damage)
Postoperative wound infection
Pyrexia (fever)

What are the common drug interactions of Bactrim Ds and Caffeine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Blood creatinine increased
Nausea (feeling of having an urge to vomit)
Vomiting

20-29:

Cough
Fall
Fistula (an abnormal connection or passageway between two)
Gastrointestinal infection (infection of stomach and intestine)
Hyperthermia (body temperature greatly above normal)
Malaise (a feeling of general discomfort or uneasiness)
Nasopharyngitis (inflammation of the nasopharynx)
Palpitations (feelings or sensations that your heart is pounding or racing)
Placenta praevia (a condition that occurs during pregnancy when the placenta is abnormally placed, and partially or totally covers the cervix)
Premature labour

30-39:

n/a

40-49:

Drug abuse
Hepatic failure (liver failure)

50-59:

Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dizziness
Migraine (headache)

60+:

Asthenia (weakness)
Cough
Dyspnoea (difficult or laboured respiration)
Oral pain
Overdose
Pyrexia (fever)
Tremor (trembling or shaking movements in one or more parts of your body)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 33.33%
Insomnia (sleeplessness): 3 people, 25.00%
Nausea (feeling of having an urge to vomit): 3 people, 25.00%
Cough: 3 people, 25.00%
Hypervigilance: 2 people, 16.67%
Fungal Infection: 2 people, 16.67%
Gastric Disorder (disease of stomach): 2 people, 16.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 16.67%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 16.67%
Headache (pain in head): 2 people, 16.67%

* Approximation only. Some reports may have incomplete information.

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