Belbuca and Abilify drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Belbuca (buprenorphine hydrochloride) and Abilify (aripiprazole). Common drug interactions include musculoskeletal disorder among females and fall among males.
The phase IV clinical study analyzes what interactions people have when they take Belbuca and Abilify. It is created by eHealthMe based on reports of 10 people who take the same drugs from the FDA, and is updated regularly.
What is Belbuca?
Belbuca has active ingredients of buprenorphine hydrochloride. eHealthMe is studying from 3,022 Belbuca users. Check the latest studies of Belbuca.
What is Abilify?
Abilify has active ingredients of aripiprazole. It is often used in depression. eHealthMe is studying from 101,454 Abilify users. Check the latest studies of Abilify.
10 people who take Belbuca and Abilify together, and have interactions are studied.

What are the common drug interactions of Belbuca and Abilify, by gender? *:
female:
- Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
- Therapeutic response unexpected
- Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
- Oligomenorrhoea (infrequent (or, in occasional usage, very light) menstruation)
- Pain in extremity
- Gait disturbance
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Back disorder
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Fatigue (feeling of tiredness)
male:
- Fall
- Tardive dyskinesia (a disorder that involves involuntary movements)
What are the common drug interactions of Belbuca and Abilify, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
- Oligomenorrhoea (infrequent (or, in occasional usage, very light) menstruation)
- Pain in extremity
- Headache (pain in head)
40-49:
- Fall
- Insomnia (sleeplessness)
- Malaise (a feeling of general discomfort or uneasiness)
- Mobility decreased (ability to move is reduced)
- Muscle strain (an injury to a muscle in which the muscle fibres tear)
- Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
- Therapeutic response unexpected
- Renal failure (kidney dysfunction)
- Chronic kidney disease
- Contusion (a type of hematoma of tissue in which capillaries)
50-59:
- Gait disturbance
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Fatigue (feeling of tiredness)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Urinary tract infection
60+:
- Fall
- Tardive dyskinesia (a disorder that involves involuntary movements)
What are the existing conditions these people have? *
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 40.00%
- Pain: 3 people, 30.00%
- Stress And Anxiety: 3 people, 30.00%
- High Blood Cholesterol: 3 people, 30.00%
- Migraine (headache): 3 people, 30.00%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 30.00%
- Inflammation: 2 people, 20.00%
- Infection: 2 people, 20.00%
- Immune System Disorder: 2 people, 20.00%
- Hypokalemia (low potassium): 2 people, 20.00%
* Approximation only. Some reports may have incomplete information.
Do you take Belbuca and Abilify?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Belbuca and Abilify:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Belbuca:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Abilify:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Belbuca and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Abilify and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Cetin, M., Celik, M., Cakici, M., Polat, M., & Suner, A, "Aripiprazole-Induced Hoarseness", Turk Psikiyatri Dergisi, 2018 Jan .
- Cetin M, Celik M, Cakici M, Polat M, Suner A, "Aripiprazole induced non-cardiogenic pulmonary edema: a case report", Turk Psikiyatri Dergisi, 2014 Dec .
- Cetin, M., Celik, M., Cakici, M., Polat, M., & Suner, A, "Aripiprazole-Induced Hoarseness", Turk Psikiyatri Dergisi, 2018 Jan .
- Cetin M, Celik M, Cakici M, Polat M, Suner A, "Aripiprazole induced non-cardiogenic pulmonary edema: a case report", Turk Psikiyatri Dergisi, 2014 Dec .
How the study uses the data?
The study uses data from the FDA. It is based on buprenorphine hydrochloride and aripiprazole (the active ingredients of Belbuca and Abilify, respectively), and Belbuca and Abilify (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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