Belsomra and Clopra drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Belsomra (suvorexant) and Clopra (metoclopramide hydrochloride). Common drug interactions include liver disorder among females and pneumonia among males.
The phase IV clinical study analyzes what interactions people have when they take Belsomra and Clopra. It is created by eHealthMe based on reports of 63 people who take the same drugs from the FDA, and is updated regularly.
What is Belsomra?
Belsomra has active ingredients of suvorexant. It is often used in insomnia. eHealthMe is studying from 12,961 Belsomra users. Check the latest studies of Belsomra.
What is Clopra?
Clopra has active ingredients of metoclopramide hydrochloride. eHealthMe is studying from 81,430 Clopra users. Check the latest studies of Clopra.
63 people who take Belsomra and Clopra together, and have interactions are studied.

What are the common drug interactions of Belsomra and Clopra, by gender? *:
female:
- Liver disorder (liver diseases)
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Neuropathy peripheral (surface nerve damage)
- Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
- Peptic ulcer
- Postoperative wound infection
- Purpura (purplish discoloration of the skin)
- Rash
- Respiratory disorder (respiratory disease)
- Stomatitis (inflammation of mucous membrane of mouth)
male:
- Pneumonia
- Platelet count decreased
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Artery dissection
- Blood pressure increased
- Renal cell carcinoma (a kidney cancer)
- Abdominal pain
- Appendicitis (inflammation of the appendix)
- Blood lactate dehydrogenase increased
- C-reactive protein increased
What are the common drug interactions of Belsomra and Clopra, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Drug abuse
40-49:
- Suicide attempt
- Cardiac failure
- Disease progression
- Hepatic failure (liver failure)
- Respiratory disorder (respiratory disease)
- Abdominal pain
- Appendicitis (inflammation of the appendix)
- Blood triglycerides increased
- Chronic kidney disease
- Decreased appetite
50-59:
- Blood pressure decreased
- Bradycardia (abnormally slow heart action)
- Chronic kidney disease
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Hypertension (high blood pressure)
- Pyrexia (fever)
- Alanine aminotransferase increased
- Aortitis (inflammation of the aortic wall)
- Axillary pain
60+:
- Decreased appetite
- Platelet count decreased
- White blood cell count decreased
- Hypokalaemia (low potassium)
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Interstitial lung disease
- Vomiting
- C-reactive protein increased
- Cardiac ventricular thrombosis (blood clot in ventricle)
- Embolism venous (embolus may pass into the arterial system)
What are the existing conditions these people have? *
- High Blood Pressure: 12 people, 19.05%
- Constipation: 9 people, 14.29%
- Pain: 9 people, 14.29%
- Hyperuricaemia (level of uric acid in the blood that is abnormally high): 7 people, 11.11%
- Sedation: 6 people, 9.52%
- Nausea (feeling of having an urge to vomit): 6 people, 9.52%
- Hyperlipidaemia (presence of excess lipids in the blood): 6 people, 9.52%
- Gastric Ulcer (stomach ulcer): 5 people, 7.94%
- Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 5 people, 7.94%
- Depression: 5 people, 7.94%
* Approximation only. Some reports may have incomplete information.
Do you take Belsomra and Clopra?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Belsomra and Clopra:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Belsomra:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Clopra:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Belsomra and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Clopra and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on suvorexant and metoclopramide hydrochloride (the active ingredients of Belsomra and Clopra, respectively), and Belsomra and Clopra (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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