Belviq and Lyrica drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Belviq (lorcaserin hydrochloride) and Lyrica (pregabalin). Common drug interactions include hypertension among females and balance disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Belviq and Lyrica. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.

What is Belviq?

Belviq has active ingredients of lorcaserin hydrochloride. It is often used in weight loss. eHealthMe is studying from 3,179 Belviq users. Check the latest studies of Belviq.

What is Lyrica?

Lyrica has active ingredients of pregabalin. It is often used in fibromyalgia. eHealthMe is studying from 261,646 Lyrica users. Check the latest studies of Lyrica.



On Jul, 31, 2026

57 people who take Belviq and Lyrica together, and have interactions are studied.

Belviq and Lyrica drug interactions.

What are the common drug interactions of Belviq and Lyrica, by gender? *:

female:

  1. Hypertension (high blood pressure)
  2. Crying
  3. Nausea (feeling of having an urge to vomit)
  4. Emotional disorder
  5. Anxiety
  6. Fatigue (feeling of tiredness)
  7. Bacteraemia (presence of bacteria in the blood)
  8. Nasopharyngitis (inflammation of the nasopharynx)
  9. Weight increased
  10. Chronic kidney disease

male:

  1. Balance disorder
  2. Grip strength decreased
  3. Renal failure (kidney dysfunction)
  4. Renal injury (kidney injury)
  5. Type 2 diabetes mellitus

What are the common drug interactions of Belviq and Lyrica, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Gait disturbance
  2. Memory impairment
  3. Sedation
  4. Speech disorder
  5. Constipation

30-39:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)

40-49:

  1. Crying
  2. Emotional disorder
  3. Chronic kidney disease
  4. Cough
  5. Fatigue (feeling of tiredness)
  6. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  7. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  8. Nephrogenic anaemia (anaemia due to kidney disease)
  9. Nervousness
  10. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

50-59:

  1. Drug ineffective
  2. Muscle spasms (muscle contraction)
  3. Depressed level of consciousness
  4. Dizziness
  5. Dry skin
  6. Fatigue (feeling of tiredness)
  7. Insomnia (sleeplessness)
  8. Nasopharyngitis (inflammation of the nasopharynx)
  9. Pancreatic carcinoma (pancreatic cancer)
  10. Pruritus (severe itching of the skin)

60+:

  1. Drug ineffective
  2. Depression
  3. Neutropenia (an abnormally low number of neutrophils)
  4. Pulmonary oedema (fluid accumulation in the lungs)
  5. Respiratory failure (inadequate gas exchange by the respiratory system)
  6. Weight increased
  7. Anaphylactic reaction (serious allergic reaction)
  8. Anxiety
  9. Appetite disorder (abnormal eating habits)
  10. Asthenia (weakness)

What are the existing conditions these people have? *

  1. Pain: 18 people, 31.58%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 14 people, 24.56%
  3. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 13 people, 22.81%
  4. Weight Decreased: 12 people, 21.05%
  5. Neuropathy Peripheral (surface nerve damage): 8 people, 14.04%
  6. Depression: 7 people, 12.28%
  7. Muscle Spasms (muscle contraction): 7 people, 12.28%
  8. High Blood Cholesterol: 7 people, 12.28%
  9. Thyroid Diseases: 6 people, 10.53%
  10. Insomnia (sleeplessness): 6 people, 10.53%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Belviq and Lyrica:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Belviq:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lyrica:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Belviq and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lyrica and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on lorcaserin hydrochloride and pregabalin (the active ingredients of Belviq and Lyrica, respectively), and Belviq and Lyrica (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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