Benadryl and Azmacort drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Benadryl (diphenhydramine hydrochloride) and Azmacort (triamcinolone acetonide). Common drug interactions include hypertension among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Benadryl and Azmacort. It is created by eHealthMe based on reports of 80 people who take the same drugs from the FDA, and is updated regularly.

What is Benadryl?

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in allergies. eHealthMe is studying from 104,955 Benadryl users. Check the latest studies of Benadryl.

What is Azmacort?

Azmacort has active ingredients of triamcinolone acetonide. It is often used in asthma. eHealthMe is studying from 3,612 Azmacort users. Check the latest studies of Azmacort.

On Aug, 04, 2026

80 people who take Benadryl and Azmacort together, and have interactions are studied.

Benadryl and Azmacort drug interactions.

What are the common drug interactions of Benadryl and Azmacort, by gender? *:

female:

Hypertension (high blood pressure)
Pain in extremity
Syncope (loss of consciousness with an inability to maintain postural tone)
Urticaria (rash of round, red welts on the skin that itch intensely)
Cough
Dry mouth
Pyrexia (fever)
Retching (strong involuntary effort to vomit)
Tinnitus (a ringing in the ears)
Urinary tract infection

male:

Anxiety
Balance disorder
Diastolic dysfunction
Dizziness
Dysaesthesia (abnormal sensation)
Dysarthria (speech disorder)
Dysphonia (speech disorder attributable to a disorder of phonation)
Dyspnoea (difficult or laboured respiration)
Fall
Gastritis (inflammation of stomach)

What are the common drug interactions of Benadryl and Azmacort, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)

10-19:

n/a

20-29:

Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Overdose

30-39:

Anaphylactic reaction (serious allergic reaction)
Dermatitis allergic (inflammation of the skin due allergic reaction)
Vomiting
Abdominal pain
Abdominal tenderness
Abnormal behaviour
Ankle fracture
Blood potassium decreased
Depression
Dyspnoea (difficult or laboured respiration)

40-49:

Nausea (feeling of having an urge to vomit)
Headache (pain in head)
Dizziness
Retching (strong involuntary effort to vomit)
Syncope (loss of consciousness with an inability to maintain postural tone)
Tinnitus (a ringing in the ears)
Vomiting
Depression
Urticaria (rash of round, red welts on the skin that itch intensely)
Weight increased

50-59:

Pain in extremity
Respiratory disorder (respiratory disease)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Suicidal ideation
Asthenia (weakness)
Chills (felling of cold)
Coma (state of unconsciousness lasting more than six hours)
Cough
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dizziness

60+:

Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Akathisia (a movement disorder characterized by a feeling of inner restlessness)
Balance disorder
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Cerebral infarction (less blood supply to brain resulting tissue damage)
Constipation
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Diabetes mellitus inadequate control
Diastolic dysfunction

What are the existing conditions these people have? *

Hypersensitivity: 9 people, 11.25%
Sleep Disorder: 8 people, 10.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 10.00%
Stress And Anxiety: 7 people, 8.75%
Multiple Allergies (allergy to multiple agents): 6 people, 7.50%
High Blood Pressure: 6 people, 7.50%
Quit Smoking: 5 people, 6.25%
Pain: 5 people, 6.25%
Muscle Spasms (muscle contraction): 5 people, 6.25%
Impaired Gastric Emptying: 5 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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